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Authors: Zerbino, Daniel R and Achuthan, Premanand and Akanni, Wasiu and Amode, M Ridwan and Barrell, Daniel and Bhai, Jyothish and Billis, Konstantinos and Cummins, Carla and Gall, Astrid and Girón, Carlos García and Gil, Laurent and Gordon, Leo and Haggerty, Leanne and Haskell, Erin and Hourlier, Thibaut and Izuogu, Osagie G and Janacek, Sophie H and Juettemann, Thomas and To, Jimmy Kiang and Laird, Matthew R and Lavidas, Ilias and Liu, Zhicheng and Loveland, Jane E and Maurel, Thomas and McLaren, William and Moore, Benjamin and Mudge, Jonathan and Murphy, Daniel N and Newman, Victoria and Nuhn, Michael and Ogeh, Denye and Ong, Chuang Kee and Parker, Anne and Patricio, Mateus and Riat, Harpreet Singh and Schuilenburg, Helen and Sheppard, Dan and Sparrow, Helen and Taylor, Kieron and Thormann, Anja and Vullo, Alessandro and Walts, Brandon and Zadissa, Amonida and Frankish, Adam and Hunt, Sarah E and Kostadima, Myrto and Langridge, Nicholas and Martin, Fergal J and Muffato, Matthieu and Perry, Emily and Ruffier, Magali and Staines, Dan M and Trevanion, Stephen J and Aken, Bronwen L and Cunningham, Fiona and Yates, Andrew and Flicek, Paul

The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of the draft human genome, with the aim of accelerating genomics research through rapid open distribution of public data. Large amounts of raw data are thus transformed into knowledge, which is made available via a multitude of channels, in particular our browser (http://www.ensembl.org). Over time, we have expanded in multiple directions. First, our resources describe multiple fields of genomics, in particular gene annotation, comparative genomics, genetics and epigenomics. Second, we cover a growing number of genome assemblies; Ensembl Release 90 contains exactly 100. Third, our databases feed simultaneously into an array of services designed around different use cases, ranging from quick browsing to genome-wide bioinformatic analysis. We present here the latest developments of the Ensembl project, with a focus on managing an increasing number of assemblies, supporting efforts in genome interpretation and improving our browser.

Journal: Nucleic acids research
DOI: 10.1093/nar/gkx1098
Year: 2018

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