July 7, 2019  |  

Complete genome sequences of nitrofurantoin-sensitive and -resistant Escherichia coli ST540 and ST2747 strains.

Authors: Xavier, Basil Britto and Vervoort, Jascha and Stewardson, Andrew and Adriaenssens, Niels and Coenen, Samuel and Harbarth, Stephan and Goossens, Herman and Malhotra-Kumar, Surbhi

Widespread multidrug resistance in Escherichia coli has necessitated the reintroduction of older antibiotics, such as nitrofurantoin. However, mechanisms by which resistance to nitrofurantoin emerges in E. coli are not well elucidated. Toward this aim, we sequenced two nitrofurantoin-sensitive E. coli sequence types (ST540 and ST2747) and their four nitrofurantoin-resistant derivatives generated in vitro under aerobic and anaerobic growth conditions.

Journal: Genome announcements
DOI: 10.1128/genomeA.00239-14
Year: 2014

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