Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
#SMRTSeq Tweet Chat: Users Weigh in on Current Applications and Future Outlook for PacBio Sequencing
Today offered something new for the PacBio® team: our SMRT® technology was the subject of a tweet chat hosted by Genome Biology. For one hour, editors at the journal along…
Single-Molecule Sequencing Technology Q&A with Nobel Laureate Rich Roberts
BioMed Central has published an interesting Q&A session on its Biome blog with Nobel Laureate Richard Roberts about why he believes in SMRT Sequencing and thinks non-users should take another…
As Cores Upgrade to PacBio RS II, Users Report Data and Progress
As PacBio customers are upgrading to the new PacBio® RS II System, some of our core lab users have already begun blogging about the improved results. At the University of…
New Genomes for 100K Pathogen Project Sequenced and Finished with PacBio Technology
The 100K Foodborne Pathogen Genome Project announced the contribution of 20 newly finished genomes of microbes responsible for foodborne disease, and we’re pleased to report that they were sequenced and…
Whole-Genome Microbial Epigenetics: ASM Workshop videos highlight emerging application of SMRT Sequencing
We recently participated in a workshop on whole-genome microbial epigenetics at the American Society for Microbiology annual meeting in Denver. Using SMRT® Sequencing, the three most common types of bacterial…
University of Oslo Scientists Use Long Reads for Unique Look at Cod Genome
Scientists at the University of Oslo’s Centre for Ecological and Evolutionary Synthesis (CEES) have used multi-kilobase sequence reads from the PacBio® RS sequencer to produce a dramatically improved genome assembly…
Genome Biology Commentary Discusses the Advantages of SMRT Sequencing
A new commentary in Genome Biology from highly respected scientific authors, including a Nobel Prize winner, highlights the benefits of Single Molecule, Real-Time (SMRT®) Sequencing. The commentary, entitled “The advantages…
Using PacBio Sequencing, Scientists Find No Evidence of Horizontal Gene Transfer in Haitian Cholera Strain
A new analysis from public health scientists has found that the cholera strain responsible for the 2010 outbreak in Haiti has a limited ability to add to its genetic repertoire…
Back from SFAF, and Eager for More Finished Genomes
Last month’s Sequencing, Finishing, Analysis in the Future (SFAF) meeting in Santa Fe, New Mexico, hosted by Los Alamos National Laboratory, attracted terrific scientists and we really enjoyed hearing about…
Two Worlds of Genome Assemblers
by Jonas Korlach, Chief Scientific Officer Finished genomes were the focus of last month’s Sequencing, Finishing, Analysis in the Future (SFAF) meeting in Santa Fe, New Mexico. In addition to…
Jonas Korlach Honored by White House as an Immigrant ‘Champion of Change’
Last week the White House held an event to honor eleven Immigrant Innovator “Champions of Change” — the best and brightest from around the world who are helping create American…
Nature Methods Paper Demonstrates a Cost-Effective Process for Finishing Genomes
A paper recently published in Nature Methods offers a deep dive into the use of our HGAP and Quiver tools to generate a high-quality genome assembly with an automated, simplified…
PNAS: Copy Number Analysis in Maize Sheds Light on Tolerance for Acidic Soil
A new study of maize sheds light on the importance of copy-number variation in genes related to stress tolerance with implications to boost crop yield in suboptimal soil environments. A…
Current Opinion in Microbiology: Bacterial Methylomes in Review – ‘An Exciting Era’
A new review paper from Brigid Davis, Michael Chao, and Matthew Waldor at Harvard Medical School considers a number of recent studies and findings that have used single molecule, real-time…
Guest Blog: Michael Schatz shares his perspective on the new PacBio RS II
Michael Schatz, Ph.D. Assistant Professor of Quantitative Biology at Cold Spring Harbor Laboratory, shares some thoughts about his experience with the PacBio RS and his hopes for future work with…