Blog
December 4, 2013
In RNA-seq Study, Long PacBio Reads Allow for Detection of Full-Length and Novel Isoforms
A new paper out in PNAS details the usefulness of long reads for isoform sequencing. “Characterization of the human ESC transcriptome by hybrid sequencing” comes from lead author Kin Fai…
December 3, 2013
PacBio Partners with Sanger Institute and Public Health England to Finish 3,000 Bacterial Genomes
Sanger’s Genome Campus We are pleased to announce a new collaboration with the Wellcome Trust Sanger Institute and Public Health England to complete the sequences of 3,000 bacterial genome strains…
November 20, 2013
New Publication Demonstrates Long-Read Sequences Needed to Thoroughly Resolve Short Tandem Repeats
In a new paper reporting a protocol for using short-read sequence data to locate short tandem repeats (STRs), scientists find that long-read sequence information is necessary to resolve regions with…
November 14, 2013
ASHG Workshop Recordings: Resolving Structural Variation in Human Genomes
We hosted a structural varation workshop at the annual meeting of the American Society of Human Genetics, and were pleased to see that the speakers’ presentations really resonated with attendees…
November 7, 2013
Event Recap: Fall User Group Meeting Presentations & Review
In September we were excited to have 100+ customers gather in Palo Alto, Calif., to discuss their use of Single Molecule, Real-Time (SMRT®) Sequencing and hear about what’s next for…
November 6, 2013
At Institute for Genome Sciences, Long Reads Offer New Path to Finished Genomes
The Genomics Resource Center (GRC) at the Institute for Genome Sciences (IGS) has a scientific pedigree and a sample-to-interpretation service commitment that place it in a league of its own….
November 4, 2013
Comparative Transcriptome Analysis: Insights from a Single SMRT Cell
In a new paper published in the journal Gene, scientists from Rutgers University and King’s College London report the use of a single SMRT® Cell to sequence and assemble more…
October 22, 2013
Data Release: Long-Read Shotgun Sequencing of a Human Genome
In order to help evaluate the utility of long, unbiased sequence reads for characterizing structural variation in the human genome using our recently released P5-C3 scaffolding sequencing chemistry, we have…
October 17, 2013
Stanford Team Finds Novel Transcripts Using Long-Read Isoform Sequencing
An advance online publication in Nature Biotechnology from Michael Snyder’s lab at Stanford University demonstrates the utility of long-read sequencing for assessing transcribed regions across the human genome. Long PacBio…
October 9, 2013
Resolving Complex Regions in the Human Genome: SMRT Sequencing Fills Major Mucin Gap
Scientists from University of North Carolina at Chapel Hill, Duke University, and other institutions have teamed up to sequence an important region of the human genome that has until now…
October 7, 2013
Characterizing Structural Variation in the Human Genome: ASHG 2013 Workshop and Presentations
We are excited to participate in the annual American Society of Human Genetics meeting again this year on October 22-26 in Boston, MA. With so many new PacBio® technology advances…
October 3, 2013
New Chemistry for PacBio RS II Provides Average 8.5 kb Read Lengths for Complex Genome Studies
Our R&D team has been focusing on chemistry improvements for the PacBio® RS II sequencer and today we are pleased to announce our newest reagent combination, the P5 DNA polymerase…
September 16, 2013
Genome Biology Paper Highlights Affordability and Scale of PacBio-Based Finished Microbial Genomes
A new paper released in Genome Biology on September 13 from lead author Sergey Koren at the National Biodefense Analysis and Countermeasures Center offers a thorough overview of SMRT® Sequencing…
September 5, 2013
Next Week’s ICG Meeting to Include Several SMRT Sequencing Talks
The International Conference on Genomics in the Americas (ICG), organized by BGI and UC Davis, is taking place on Sept 12-13 in Sacramento, CA. One of the keynote presentations in…
September 3, 2013
New Data Release: Arabidopsis Assembly Offers Glimpse of
De Novo SMRT Sequencing for Larger Genomes
Update 1/13/14: A new data release of Arabidopsis using P5-C3 chemistry is available Advances in our chemistries, throughput, and read length are pushing the envelope in the way we tackle…