Blog
May 13, 2014
A New Approach for HLA Typing: SMRT Sequencing
Two recent news announcements demonstrate the utility of our Single Molecule, Real-Time (SMRT®) Sequencing technology in the challenging realm of HLA typing. HLA typing — or analysis of genes in…
May 6, 2014
Retroviral Study Reveals Potential for Influencing HIV Replication
Scientists from the Icahn School of Medicine at Mount Sinai in New York City and the MRC National Institute for Medical Research in London published a paper using Single Molecule,…
May 5, 2014
Webinar Recap: New Insights in Genome and Transcriptome Research
This week, our CSO Jonas Korlach hosted a webinar entitled “Gain New Insights in Genome and Transcriptome Research with Greater than 10,000 bp Reads.” He spoke to attendees about the…
April 24, 2014
SMRT Sequencing of Chicken Heart Transcripts Yields New Genes and Isoforms
The Gallus gallus (common chicken) genome was initially published in 2004, but the latest RefSeq and Ensembl annotations remain incomplete. The chicken is an important model organism, especially for research…
April 16, 2014
Innovation Centre in Quebec Uses SMRT Sequencing for
Cost-Effective, Complete Microbial Genomes
At the McGill University and Génome Québec Innovation Centre, many projects conducted in the sequencing core facility fall under the umbrella of life sciences rather than biomedical research. To the…
April 10, 2014
Webinar Recap: Automating PacBio 10 kb template preparation
During our recent sample prep webinar, PacBio® scientists described new automated options for the 10 kb SMRTbell™ template preparation workflow. In case you didn’t have the chance to attend, here’s…
April 8, 2014
GC-Rich Genome of Pandoraea Bacterium Assembled with SMRT Sequencing
Scientists from the Institute of Biological Sciences at the University of Malaya recently published a description of Pandoraea sp. strain RB-44 in Genome Announcements, a journal from the American Society…
April 2, 2014
FDA-Supported Pathogen Database to Expand with SMRT Sequencing
We’re delighted to report that Single Molecule, Real-Time (SMRT®) Sequencing will be a crucial technology in a new research program conducted by the University of Maryland School of Medicine. The…
April 1, 2014
Deep Thoughts by Ken Dewar from McGill University
Scientist Ken Dewar from McGill University discusses his vast expertise in next-generation sequencing, some little-known facts about the launch of the 454 platform, and a revolutionary business idea for researchers…
March 31, 2014
New Software Release: SMRT Analysis Upgrade for Iso-Seq Analysis and HLA Allele Phasing
Today we announced the release of a software upgrade for our Single Molecule, Real-Time (SMRT®) DNA Sequencing platform. SMRT Analysis 2.2 provides enhanced functionality to support two additional applications that…
March 31, 2014
This Week: Sample Prep Webinar on 10 Kb Template Prep
If you love long reads, you won’t want to miss this week’s webinar on sample prep for Single Molecule, Real-Time (SMRT®) Sequencing. We will focus on automation solutions for 10…
March 27, 2014
As Genome Editing Gains Traction, SMRT Sequencing Provides Accurate View of Results
A new paper published in Cell Reports describes how Single Molecule, Real-Time (SMRT®) Sequencing can be used to greatly improve outcome reporting for a variety of popular genome-editing approaches. “Quantifying…
March 26, 2014
Importance of Finished Microbial Genome Highlighted for Ethanol-Generating Clostridium
A paper in BioMed Central’s Biotechnology for Biofuels journal demonstrates how finished microbial genomes using Single Molecule, Real-Time (SMRT®) Sequencing are having an impact on the biotechnology industry. The publication,…
March 21, 2014
ABRF Preview: Off to the Land of Core Labs and Hot Air Balloons
Members of the PacBio team will be heading down to Albuquerque this weekend for the annual conference of the Association of Biomolecular Resource Facilities (ABRF). It’s a big year for…
March 19, 2014
Assessment of Highly Complex Alternative Splicing of Neurexins Performed with SMRT Sequencing
A new paper in the Proceedings of the National Academy of Sciences from the laboratories of Stephen R. Quake and Thomas C. Südhof (both at Stanford University) describes the direct,…