Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
Plant and Animal Genomes: New Web Resource Available
After so many compelling customer projects for microbial genomes, it’s been rewarding to see more scientists turning to Single Molecule, Real-Time (SMRT®) Sequencing for larger genomes, such as plants and…
Novel Study of Genome-wide PT Modifications in Bacteria Performed with SMRT Sequencing
A recent paper from scientists in China and the United States demonstrates a novel view of phosphorothioate (PT) DNA modifications in two bacterial genomes. Scientists from Shanghai Jiao Tong University,…
At ISMB, Gene Myers’ Keynote Offers History, Future of Genome Assembly
At ISMB 2014 in Boston earlier this month, Gene Myers of the Max-Planck Institute for Molecular Cell Biology and Genetics, presented a keynote address entitled “DNA Assembly: Past, Present, and…
ISMB 2014: The World Cup of Bioinformatics
We’re eager for the #ISMB conference — it’s the 22nd annual Intelligent Systems for Molecular Biology event — kicking off this weekend in Boston. As we continue to push our…
Optimizing Eukaryotic De Novo Genome Assembly: Webinar Recording Available
Our webinar on eukaryotic genome assembly attracted a great crowd, and now we’re making the full recording available to the community. The session featured great hands-on information and best practices…
Scientists Generate the First Personal Transcriptome Using SMRT Sequencing
A new paper from scientists at Stanford University and Yale University describes the use of Single Molecule, Real-Time (SMRT®) Sequencing to generate transcriptomes for three individuals. The work is believed…
At SFAF 2014, Great Science and High-Quality Genomes
It’s been a busy start to the summer, but we’re still basking in the top-notch presentations and posters from the Sequencing, Finishing, and Analysis in the Future meeting last month….
Unprecedented Read Length at the Icahn Institute:
Precise Sizing + SMRT Sequencing
At the Icahn Institute for Genomics and Multiscale Biology at Mount Sinai in New York City, technology development expert Robert Sebra, Ph.D., sees tremendous need for long-read, high-accuracy sequencing for…
ARCHIVED: Intro to the Iso-Seq Method: Full-length transcript sequencing
Since the launch of the Iso-Seq protocol in SMRT Analysis in 2014, the analysis pipeline has seen several improvements, as well a host of new tools. Please see our updated…
Research Studies Use Sequencing to Track Path of Infection Outbreaks
A talk at last week’s ASM conference continued the recent trend of scientists using Single Molecule, Real-Time (SMRT®) Sequencing in research projects designed to better understand the transmission path of…
The Sequence Analysis Meeting: SFAF 2014
The Sequencing, Finishing, and Analysis in the Future (SFAF) meeting kicks off today in Santa Fe, New Mexico. The conference is hosted by Los Alamos National Laboratory and focuses on…
At ASM, Pioneering Scientists Presented Bacterial Methylome Highlights
This week’s annual meeting of the American Society for Microbiology was every bit as interesting, data-rich, and jam-packed as promised. We’re grateful to everyone who stopped by our booth and…
American Society for Microbiology (ASM) Preview –
SMRTest Microbe Grant Program
We’re getting ready for next week’s annual meeting of the American Society for Microbiology. Thousands of microbiologists from around the world will be gathering in Boston for the event, which…
A New Approach for HLA Typing: SMRT Sequencing
Two recent news announcements demonstrate the utility of our Single Molecule, Real-Time (SMRT®) Sequencing technology in the challenging realm of HLA typing. HLA typing — or analysis of genes in…
Retroviral Study Reveals Potential for Influencing HIV Replication
Scientists from the Icahn School of Medicine at Mount Sinai in New York City and the MRC National Institute for Medical Research in London published a paper using Single Molecule,…