Blog
July 23, 2015
SMRT Sequencing Provides Novel View of Long-Term Viral Evolution in a Single Patient
A group of scientists from the University of Pittsburgh School of Medicine and New York University used long-read sequencing from PacBio for a remarkable new study characterizing influenza virus evolution…
July 21, 2015
Webinar: Anthony Nolan’s Neema Mayor Reports on HLA Typing with Long Reads
Following the recent paper about HLA typing from scientists at Anthony Nolan Research Institute, we thought readers might enjoy this webinar from Neema Mayor, a scientist at the institute and…
July 14, 2015
SMRT Sequencing Contributes to Detection of DNA Methylation in C. elegans
A recent paper in the journal Cell presents novel findings of DNA methylation in C. elegans, an organism previously believed not to have such epigenetic marks. Scientists used several approaches…
July 9, 2015
The Festival of Genomics Review: A Celebration of Long Reads
At the inaugural Festival of Genomics event in Boston, more than 1,500 people turned out to see what was billed as a conference unlike any other. The meeting was indeed…
June 29, 2015
Nature Methods Paper Uses Long-Read Data for Highly Contiguous Diploid Human Genome
A new publication in Nature Methods describes a new single-molecule assembly approach that resulted in “the most contiguous clone-free human genome assembly to date,” according to lead authors Matthew Pendleton,…
June 25, 2015
SMRT Data Delivers for Next-Generation HLA Typing at Anthony Nolan Research Institute
A new publication in PLoS One from authors at Anthony Nolan’s Research Institute describes a feasibility study for HLA typing using SMRT® Sequencing. The research institute, where the world’s first…
June 15, 2015
Scientists Publish New Methylation Analysis Protocols Using SMRT Sequencing
Scientists from the Icahn School of Medicine at Mount Sinai and the University of Saskatchewan teamed up to develop an innovative approach to methylation analysis using Single Molecule, Real-Time (SMRT®)…
June 11, 2015
Updated! Data Release: Human MCF-7 Transcriptome
UPDATE: Our R&D team has added a new dataset for the MCF-7 human breast cancer transcriptome, originally released in 2013. The new results were produced using 28 SMRT® Cells with…
June 9, 2015
Attend Our Worldwide User Meetings & SMRT Informatics Developers Conference
If you’d like to hear about the latest applications of SMRT® Sequencing from users, we have several events coming up. Our worldwide user group meetings and workshops feature PacBio users…
June 2, 2015
In Assembler Evaluation, Scientists Recommend Non-hybrid Approach to Bacterial Genomes
A new publication in Nature Scientific Reports recommends using only the PacBio® system to sequence bacterial genomes for the best chance of generating an accurate and finished assembly. The paper,…
May 28, 2015
Microbial Madness: Talks, Posters, and SMRTest Microbe Grant Program at ASM 2015
For some people, Mardi Gras and beignets are big attractions in New Orleans — but for us it’s all about the annual conference of the American Society for Microbiology. With…
May 26, 2015
New MHAP Algorithm Delivers Fast, High-Quality Genome Assemblies
A new publication in Nature Biotechnology reports the development of a lightning-fast genome assembly pipeline optimized for long reads. Scientists from the University of Maryland and the National Biodefense Analysis…
May 6, 2015
Tutorial on the Iso-Seq Method: Applications, Protocol, and Experimental Design
If you missed our recent webinar on isoform sequencing with the PacBio® platform, we’ve made the full recording available for on-demand access. “Iso-Seq™ Method: Sample Prep and Experimental Design for…
May 4, 2015
PAG Grant Winner: Rainforest Tree Homalanthus nutans to get the SMRT Treatment
We’re pleased to announce the winner of our recent “Most Interesting Genome in the World” grant competition. Congratulations to Jay Keasling and Jeff Wong at the University of California, Berkeley!…
April 30, 2015
In Study, Continuous Long Reads Outperform Synthetic Long Reads for Resolving Tandem Repeats
Scientists from Argentina and Brazil published the results of a study comparing long-read approaches to characterize the genome structure of a highly complex region of the Y chromosome in Drosophila…