Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
PMWC 2016: Advancing Genomics for Improved Patient Care
We’re already looking forward to next month’s Personalized Medicine World Conference. Long before “precision medicine” was an industry catchphrase, PMWC was bringing together stakeholders from genomics companies and academic research,…
Scientists Use the Iso-Seq Method to Study Genes Linked to Prostate Cancer
A team of scientists from Australia, Canada, and the US published fascinating new work that may help explain gene expression patterns seen in prostate cancer. In the course of the…
Scientists Publish High-Quality, Near-Complete Genome of Resurrection Grass Oropetium
We’re excited about a new Nature paper from the winners of our 2014 “Most Interesting Genome in the World” SMRT Grant program. “Single-molecule sequencing of the desiccation tolerant grass Oropetium…
Steven Marsh from Anthony Nolan Discusses the Past and Future of Donor Matching
Mendelspod host Theral Timpson recently interviewed Professor Steven Marsh, Director of Bioinformatics at the Anthony Nolan Research Institute, a UK-based organization dedicated to improving the outcomes of bone marrow transplantation…
Welcome to Silicon Valley, Festival of Genomics!
This week the Festival of Genomics comes to the West Coast, and we’re excited to be a founding sponsor of the Front Line Genomics organization. Not only is it our…
Scientists Sequence Klebsiella Strain Resistant to All Known Antibiotics
A new publication reports the discovery and analysis of a nightmare bacterium that’s genetically resistant to all commercially available classes of antibiotics. The paper, “Stepwise evolution of pandrug-resistance in Klebsiella pneumonia,”…
Guest Blog: Rich Roberts Urges Scientists to ‘Think Methylation’ in Microbial Sequencing
Richard Roberts, Nobel Laureate and Chief Scientific Officer of New England Biolabs, offers his thoughts on the utility of methylation data for understanding prokaryotes. In his words: “Please run SMRT…
Scientists Reveal Recent Autosome-to-Y Duplication Event in Drosophila
Following on the heels of characterizing 18 Mst77Y genes that were tandemly duplicated within a 96 kb region (Krsticevic FJ, et al., 2015), scientists from institutes in Brazil, Austria, and the…
ASHG 2015: Highlights from the Platinum Genome Session and More
During the final days of the ASHG meeting last week in Baltimore, a number of scientists offered great presentations based on data generated with SMRT Sequencing, including an entire session…
ASHG 2015: Highlights from Icahn Institute, UW, Stanford & CSHL Presentations
During the Wednesday afternoon sessions of last week’s ASHG conference, several speakers provided helpful insights about their use of SMRT Sequencing for a range of applications. Highlights included the following:…
ASHG Workshop Recap & Recording: Addressing Hidden Heritability with SMRT Sequencing
The PacBio workshop at ASHG 2015 featured talks from two leaders in human genomics, Rick Wilson of Washington University and Richard Gibbs from Baylor University. Mike Hunkapiller, CEO of Pacific…
ASHG 2015 Workshop Live Stream
Watch a recording of our AGBT 2015 workshop, “Addressing Hidden Heritability with Long-Read Single Molecule, Real-time (SMRT) Sequencing”:
Beyond the $1,000 Genome: An Interview with Mark Gerstein
Next-generation sequencing has many people excited about the prospect of the $1,000 genome, however recent discoveries show that short-read sequencing technologies miss important genomic elements, driving scientists to look for…
Toward Platinum Genomes: PacBio Releases a New, Higher-Quality CHM1 Assembly to NCBI
As part of our effort to support the National Institutes of Health and the Genome Reference Consortium (GRC) in creating platinum genomes for the research community and improving the reference…
ASHG 2015: Workshop, Presentations, and First Chance to See the Sequel System
We’re looking forward to the year’s biggest scientific meeting focused on human genetics next week — the American Society of Human Genetics (ASHG) 2015 annual meeting, taking place in Baltimore,…