Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
Eco-friendly Soil Remediation Gets a Boost with the Latest SMRT Grant Program Winner
Congratulations to the winner of the first-ever SMRT Grant program decided by the community: Renying Zhuo of the Chinese Academy of Forestry! We ran polling through our Genome Galaxy Initiative…
Join the SMRT Community: User Meetings in Europe, Asia, and the US
There are several PacBio user meetings coming up, and with locations around the world we hope you’ll be able to attend one of them. These meetings are a great way…
Upcoming Webinars on Biomedical Research, Data Analysis, and Structural Variation
We’ve got several educational webinars coming up, and we hope you can join us! Our first event will be hosted by Front Line Genomics on April 28 (4:00 p.m. BST…
On DNA Day Honoring Discoveries – Y chromosome, Reference Grade De Novo Assemblies & Methylation
Happy DNA Day, everyone! This scientific celebration has us reflecting on the many advancements the community has made in the past year. For a molecule that is sequenced thousands of…
Benchmarking Study:
Full-Length 16S Sequencing Offers Better Phylogenetic Resolution
Scientists from the Joint Genome Institute and other institutions recently reported a new SMRT Sequencing approach to microbial profiling using full-length sequencing of the 16S rRNA gene. In a benchmarking…
First Comprehensive Analysis of Mosquito Y Chromosome Offers Clues for Vector Control
A new PNAS paper offers the first detailed analysis of the Anopheles gambiae Y chromosome, which could prove critical for biological and infectious disease research. The report uncovered extensive remodeling…
Japanese Scientists Find Gene Fusion Driving B Cell Leukemia
In a new Nature Genetics paper, scientists from the University of Tokyo and several other Japanese institutes and hospitals present results of a sweeping study of gene fusions driving a…
Accelerating Cancer Research Discovery with SMRT Sequencing at AACR 2016
The PacBio team is gearing up for the annual meeting of the American Association for Cancer Research (AACR), which will be held April 16-20 in New Orleans. We’re looking forward…
Genome and Transcriptome Analysis Help Scientists Deconstruct Cancer Complexity
At Cold Spring Harbor Laboratory, scientists used SMRT® Sequencing to decode one of the most challenging cancer genomes ever encountered. Along the way, they built a portfolio of open-access analysis…
From Earthworms to Alpacas: Vote Now to Choose the Next SMRT Grant Program Winner!
For the first time ever, the winner of this year’s “Explore Your Most Interesting Genome” SMRT Grant program will be decided by the community. We’ll be using our new Genome…
With Greater Contiguity, New Gorilla Genome Assembly Offers Insights into Gene Content, SVs, and More
In a Science paper published today, scientists from the University of Washington, the McDonnell Genome Institute, and other organizations present a new gorilla genome assembly generated with PacBio long-read sequencing,…
New Study Uses SMRT-ChIP Method to Find Novel Methylation in Mouse Embryonic Stem Cells
In a new Nature publication, scientists from Yale and other institutions report the discovery of N6-methyladenine (N6-mA) in mouse embryonic stem cells (ESCs), contrary to the conventional wisdom that the…
CSHL Scientists Discuss Long-Read Sequencing for More Contiguous Assemblies and Complex Genomes
Much like the “sharpen” tool in Photoshop brings a picture into tighter focus and enhances the fine detail, long-read sequencing offers enhanced resolution of genomic information, according to Cold Spring…
Genome Galaxy Initiative:
On a Mission to Sequence the Beautiful and Mysterious Kākāpō
New Zealand is more than an amazing vacation destination or the setting of the Lord of the Rings movies; it’s also home to a wealth of fascinating species that evolved…
Prevalent Methylation in Prokaryotic Genomes Suggests Regulatory Functions
A new publication from scientists at Lawrence Berkeley National Laboratory, the Joint Genome Institute, and other organizations reports a landmark study of genome-wide methylation in prokaryotes. The analyses of 230…