Blog
August 20, 2026
SPRQ-Nx on Vega raises the bar for benchtop HiFi sequencing
PacBio began shipping SPRQ-Nx chemistry for the Vega system this week, a launch that meaningfully expands what benchtop HiFi sequencing can do. A companion software update arrives alongside it,…
August 17, 2026
Customer success story:
How Uppsala University and the Genome of Sweden project are scaling national genomics projects with Revio and SPRQ-Nx
When Dr. Adam Ameur first encountered long-read sequencing data, the idea of sequencing thousands of complete human genomes with long reads seemed distant. Back in 2013, he was using…
August 13, 2026
How long-read sequencing builds the foundation for AI-driven biopharma
Artificial intelligence is reshaping nearly every stage of drug discovery and development. From identifying new therapeutic targets to predicting protein function, designing therapeutics, and improving patient stratification, AI has…
August 10, 2026
Measuring – not guessing – the true path
Over the past ~15 years, several attempts were made to adapt short-read sequencing to capture longer-distance information, including 10X Genomics linked reads, Illumina TruSeq synthetic long reads, and Illumina…
August 6, 2026
Customer success story:
How CHU Nîmes went from install to routine rare disease use in three months
For many genetics labs, the road from instrument installation to routine use consists of long months of validation, workflow development, and institutional sign-off. Dr. Claire Guissart, head of the…
July 30, 2026
APAC PRISM 2026 highlights: Advancing research with HiFi sequencing
We are excited to share highlights from the 2026 APAC PRISM event, held this year in Fukuoka, Japan. Located near Canal City, this PRISM event offered attendees the opportunity…
July 28, 2026
The practical value of long-range PCR for targeted HiFi sequencing
For clinical research laboratories evaluating long-read sequencing, the central question is often not whether longer reads are useful. The value is clearest in the places where conventional approaches have…
July 23, 2026
Meet the winner of the 2026 SMRT Grant for long-read cancer multiomics for clinical research and drug discovery
Cancer genomics is one of the most complex and consequential areas in all of life sciences. The genetic and epigenetic changes that drive tumor development, progression, and treatment resistance…
July 16, 2026
Why long reads are changing how researchers approach targeted sequencing
In genomics, every lab is chasing the same trio of workflow priorities: working toward results that are accurate, flexible in application, and efficient in practice. For labs focused on…
July 9, 2026
FDA draft guidance highlights the growing importance of long-read sequencing for genome editing safety assessment
Genome editing technologies are transforming the development of next-generation therapeutics. From CRISPR-Cas systems to base and prime editors, these approaches offer unprecedented opportunities to correct disease-causing mutations and engineer…
July 2, 2026
Powered by PacBio:
Selected publications from April – June 2026
This quarter’s publications are showing us where genomics is headed: from incomplete views of the genome toward comprehensive, genome-wide analysis. Across population genomics, clinical whole-genome sequencing, and medical genetics,…
June 25, 2026
Rapid HiFi whole genome sequencing for time-critical genomic research
In time-critical settings, like a neonatal intensive care unit, the pressure to find explanations is immediate. For example, an estimated 60% of level IV NICU infants in the US…
June 16, 2026
Exploring the epigenome of Earth’s biodiversity: From CHG and CHH methylation to Fiber-seq
Sequencing has transformed our ability to study genetic variation across the tree of life, but DNA sequence alone does not explain how biological traits emerge. The same genome can…
June 11, 2026
The practical questions clinical research labs consider when adopting HiFi sequencing
For clinical laboratories evaluating long-read sequencing, the central question has changed. A substantial and growing body of research now demonstrates that HiFi sequencing can deliver the accuracy, comprehensiveness, and…
June 4, 2026
The microbial world is everywhere. Long-read sequencing is finally allowing us to see it clearly.
Microbes account for most of the diversity of life on our planet, yet fewer than 1% have been identified. They drive human health and disease, shape agriculture, cycle nutrients…