Blog
October 12, 2022
2022 Cancer Transcriptomics SMRT Grant winners
At PacBio, we are driven to create the most sophisticated multiomic sequencing technologies so that you can forge a new frontier in cancer research. Through the SMRT Grant program, PacBio awards free…
October 10, 2022
Enabling research in pharmacogenomics
In the drive for precision medicine, enabling pharmacogenomics (PGx) research to investigate how an individual’s genetic variants can impact their response to medication is critical. With robust coverage of difficult-to-sequence…
September 30, 2022
The HiFi difference — not being CLR
This week Illumina gave an update on their synthetic long-read approach previously named “Infinity reads,” now rebranded as Complete Long Reads (CLR). This acronym choice is of course quite ironic…
September 27, 2022
2022 HiFi for Accuracy SMRT Grant winners
PacBio is pleased to present the recipients of this year’s HiFi for accuracy SMRT grant. At PacBio, we are driven to create the most accurate genomic sequencing technologies so that you…
September 20, 2022
AGBT Precision Health 2022: A look at coming advancements in genomic medicine
The PacBio team recently attended the AGBT (Advances in Genome Biology and Technology) Precision Health conference in San Diego, Calif. This was the seventh year of the conference, and it…
September 14, 2022
Cost-effective microbiome and metagenomic HiFi sequencing with PacBio service providers
Full-length 16S and shotgun metagenome HiFi sequencing with certified PacBio service providers can deliver remarkably affordable microbiome and metagenomic data with explanatory power that is second to none. Gaps, assembly…
September 8, 2022
The HiFi difference – E pluribus unum
Over the past few months, we have highlighted the striking versatility of HiFi sequencing in a series of a dozen blogposts, allowing many different research applications to be performed with…
September 1, 2022
Thwart food-borne contaminants with the extraordinary accuracy of HiFi sequencing
HiFi sequencing delivers the most accurate and comprehensive microbial sequence data possible to give food safety and public health professionals the clarity they need to better understand contaminants and make…
August 26, 2022
The HiFi difference – delivering superior data for proteogenomics
In living cells, it is typically the proteins that are the work horses of carrying out the myriad of biological functions, and that can be subject to aberrant processes that…
August 25, 2022
HiFi sequencing delivers a cutting-edge view of RNA isoforms in cancer
Olga Anczukow (@OlgaAnczukow), PhD, a leading expert on breast cancer at the Jackson Laboratory, recently presented on how HiFi sequencing (PacBio’s highly accurate long-read sequencing technology) with the Iso-Seq method…
August 10, 2022
The HiFi difference: powering biodiversity genomics
In a new preprint, entitled Realizing the promise of biodiversity genomics with highly accurate long reads, a group of researchers from Utah State, BYU, the LOEWE Centre for Translational Biodiversity…
August 3, 2022
The HiFi difference: resolving the most complex genomic regions
The combined accuracy, read length, and coverage uniformity of PacBio HiFi sequence reads enables the characterization of many previously inaccessible regions in the genome. Two new preprints by Oscar Rodriguez,…
July 22, 2022
The HiFi difference: enabling the human pangenome reference
A few weeks ago, we described the use of HiFi sequencing to drive the paradigm shift from a single reference genome to a pangenome derived from a diverse set of…
July 20, 2022
HiFi sequencing tools to help transform AAV-based gene therapy
Leading researchers in AAV-based gene therapy development recently presented how they are leveraging PacBio long-read sequencing technology to advance product design and performance. Background Building treatments for individuals…
July 15, 2022
5 weeks, 20 cities, countless connections: Discoveries Roadshow 2022
This spring, leading life science experts from 26 countries gathered at PacBio organized events to discuss exciting developments in HiFi sequencing technology, explore new genomic applications, and foster human…