Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
Powered by PacBio: Selected publications for November 2023
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
A HiFi movement: Transcript isoform resolved RNA sequencing
The books of life are fascinating yet challenging reads, owing to the complexity of the underlying biological processes and their alterations that lead to disease. Thanks to highly accurate HiFi…
Sequencing 101: Tandem repeats
In the field of genetics, the concept of tandem repeats has been both scientifically fascinating, experimentally challenging, and motivating for technology development. As DNA sequencing technologies and analysis tools have…
Empowering the pharmacogenomics research community with long-read sequencing
The power of pharmacogenomics (PGx) panel testing PGx aims to understand how individual genetic differences influence drug response, enabling personalized medicine research. While several amplicon studies have shown the…
Capturing human genomic diversity
A new Arab pangenome reference has been constructed from 43 individuals enabling the study of variants and sequences of significance to the Arab population. In a newly released preprint entitled…
Powered by PacBio: Selected publications for October 2023
PacBio HiFi sequencing technology continues to play an increasingly pivotal role in advancing critical research across the life sciences. In this blog series, we explore some of the latest and…
Revio metagenomics + Kinnex 16S data release demonstrate futuristic microbiome capabilities
Microbiology forms the bedrock of modern genetics and biotechnology. Whether its basic science, alternative energy development, drug discovery, or human health – our planet’s smallest organisms play a critical role…
Powered by PacBio: Selected publications for September 2023
PacBio HiFi sequencing technology continues to play an increasingly pivotal role in advancing critical research across the life sciences. In this blog series, we explore some of the latest and…
Into the multiome: Four high-quality ‘omes from a single Revio SMRT Cell run
As Marvel superheroes traverse the multiverse to save the day, genomics researchers are our superheroes as they navigate the daunting multiverse that is biology. The complex and dynamic interactions between…
HiFi sequencing enables researchers to complete and analyze the Y chromosome
PacBio HiFi long-read sequencing is one of the most advanced sequencing technologies for generating groundbreaking discoveries that can expand our understanding of human health. In case you missed it, we…
Powered by PacBio: Selected publications for August 2023
Want to know what PacBio users have been up to? In this summary, get the latest on some of the hottest scientific publications to incorporate PacBio sequencing methods. Selections from…
Iso-Seq method outperforms other long-read methods in benchmarking consortium study
A benchmarking of long-read RNA sequencing methods and analysis tools The Long-read RNA-Seq Genome Annotation Assessment Project (LRGASP) consortium, an initiative to systematically evaluate methods for transcript identification and quantification,…
Why SBB could be a game-changer for liquid biopsy research
Onso short-read sequencing systems are no longer available through PacBio PacBio HiFi long-read sequencing technology has made huge strides in helping us understand tumor biology, from the ability to call…
Faster and more affordable sequencing with the HiFi microbial high-throughput workflow
Highly-accurate HiFi reads produced by PacBio long-read sequencers –such as the Sequel IIe and Revio systems– enable researchers to access entirely new levels of contiguity, completeness, and accuracy when assembling…
Sequencing 101: SBB sequencing
Onso short-read sequencing systems are no longer available through PacBio Since the inception of next generation sequencing (NGS) more than a decade ago, short-read sequencing accuracy has seen only marginal…