Blog
January 9, 2024
Highly accurate sequencing enables the detection of microsatellite instability associated with cancer
Onso short-read sequencing systems are no longer available through PacBio In the complex landscape of cancer biology, the exploration of microsatellite instability (MSI) has emerged as a promising frontier, offering…
January 4, 2024
Mastering AAV vector design: Best practices for gene therapy product characterization using HiFi sequencing
By Claire Aldridge, PhD Dr. Aldridge, Chief Strategy Officer at Form Bio, pioneers advanced pharmaceutical solutions to get life-saving therapeutics to patients. She was recently selected as one of Forbes’…
December 28, 2023
Our favorite publications of 2023
2023 has been an incredible year for genomics! Thanks to the brilliance and scientific talent of researchers all over the world, major progress was made across the board –from agrigenomics…
December 21, 2023
High-quality genomes for a biodiverse Christmas
After last year’s humongous achievement of assembling the 100 Gb mistletoe genome, it is very exciting to see many more holiday associated species assembled by the Darwin Tree of Life…
December 19, 2023
Sequencing 101: Structural variation
Over the last 50 years, many monumental achievements in genetics and biology have unfolded before our eyes. From the invention of DNA sequencing technologies to the completion of the human…
December 12, 2023
Kinnex launch promises to revolutionize RNA research
RNA sequencing (RNA-seq) has become an indispensable tool for analyzing transcriptomes across all domains of life that can reveal insights about biology and disease. While the genome remains relatively constant…
December 7, 2023
Powered by PacBio: Selected publications for November 2023
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
November 30, 2023
A HiFi movement: Transcript isoform resolved RNA sequencing
The books of life are fascinating yet challenging reads, owing to the complexity of the underlying biological processes and their alterations that lead to disease. Thanks to highly accurate HiFi…
November 22, 2023
Sequencing 101: Tandem repeats
In the field of genetics, the concept of tandem repeats has been both scientifically fascinating, experimentally challenging, and motivating for technology development. As DNA sequencing technologies and analysis tools have…
November 15, 2023
Empowering the pharmacogenomics research community with long-read sequencing
The power of pharmacogenomics (PGx) panel testing PGx aims to understand how individual genetic differences influence drug response, enabling personalized medicine research. While several amplicon studies have shown the…
November 9, 2023
Capturing human genomic diversity
A new Arab pangenome reference has been constructed from 43 individuals enabling the study of variants and sequences of significance to the Arab population. In a newly released preprint entitled…
November 7, 2023
Powered by PacBio: Selected publications for October 2023
PacBio HiFi sequencing technology continues to play an increasingly pivotal role in advancing critical research across the life sciences. In this blog series, we explore some of the latest and…
November 1, 2023
Revio metagenomics + Kinnex 16S data release demonstrate futuristic microbiome capabilities
Microbiology forms the bedrock of modern genetics and biotechnology. Whether its basic science, alternative energy development, drug discovery, or human health – our planet’s smallest organisms play a critical role…
October 16, 2023
Powered by PacBio: Selected publications for September 2023
PacBio HiFi sequencing technology continues to play an increasingly pivotal role in advancing critical research across the life sciences. In this blog series, we explore some of the latest and…
September 27, 2023
Into the multiome: Four high-quality ‘omes from a single Revio SMRT Cell run
As Marvel superheroes traverse the multiverse to save the day, genomics researchers are our superheroes as they navigate the daunting multiverse that is biology. The complex and dynamic interactions between…