Blog
February 21, 2024
Watch: Kinnex kits enable full-length 16S and RNA sequencing at scale
When new sequencing instruments are released, great leaps in genomics capabilities follow. But did you know that for some applications like 16S microbiome research, gene annotation, or cancer transcriptomics, “new-instrument-level” performance can be achieved with something as simple as an off-the-shelf kit?
February 20, 2024
Rare disease research. Can HiFi sequencing help shorten the journey to answers?
According to the United States’ National Institutes of Health (NIH), an estimated 7,000 rare diseases collectively impact between 3.5% to 5.9% of the global population, equating to 263 to 446…
February 13, 2024
Powered by PacBio: Selected publications from January 2024
Coming to you a little late out of the gate, this edition of Powered by PacBio includes some hot publications from this past month including: a powerful new metagenome assembler, a long-read wheat pan-transcriptome, and two papers delving into cancer biology. Take a look!
February 7, 2024
2023 gene therapy research STAR Grant winners announced
In 2023, PacBio selected five up-and-coming gene therapy researchers to receive our STAR Grant award which provides sequencing assistance and a travel stipend to present a PacBio sponsored event. Check out our winners and their projects!
February 2, 2024
Winning proposals for 2023 PacBio grants announced
At PacBio we are obsessively motivated to create the most powerful long and short-read sequencing technologies in the world — so that you can shatter the status quo and forge…
January 9, 2024
Highly accurate sequencing enables the detection of microsatellite instability associated with cancer
Onso short-read sequencing systems are no longer available through PacBio In the complex landscape of cancer biology, the exploration of microsatellite instability (MSI) has emerged as a promising frontier, offering…
January 4, 2024
Mastering AAV vector design: Best practices for gene therapy product characterization using HiFi sequencing
By Claire Aldridge, PhD Dr. Aldridge, Chief Strategy Officer at Form Bio, pioneers advanced pharmaceutical solutions to get life-saving therapeutics to patients. She was recently selected as one of Forbes’…
December 28, 2023
Our favorite publications of 2023
2023 has been an incredible year for genomics! Thanks to the brilliance and scientific talent of researchers all over the world, major progress was made across the board –from agrigenomics…
December 21, 2023
High-quality genomes for a biodiverse Christmas
After last year’s humongous achievement of assembling the 100 Gb mistletoe genome, it is very exciting to see many more holiday associated species assembled by the Darwin Tree of Life…
December 19, 2023
Sequencing 101: Structural variation
Over the last 50 years, many monumental achievements in genetics and biology have unfolded before our eyes. From the invention of DNA sequencing technologies to the completion of the human…
December 12, 2023
Kinnex launch promises to revolutionize RNA research
RNA sequencing (RNA-seq) has become an indispensable tool for analyzing transcriptomes across all domains of life that can reveal insights about biology and disease. While the genome remains relatively constant…
December 7, 2023
Powered by PacBio: Selected publications for November 2023
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
November 30, 2023
A HiFi movement: Transcript isoform resolved RNA sequencing
The books of life are fascinating yet challenging reads, owing to the complexity of the underlying biological processes and their alterations that lead to disease. Thanks to highly accurate HiFi…
November 22, 2023
Sequencing 101: Tandem repeats
In the field of genetics, the concept of tandem repeats has been both scientifically fascinating, experimentally challenging, and motivating for technology development. As DNA sequencing technologies and analysis tools have…
November 15, 2023
Empowering the pharmacogenomics research community with long-read sequencing
The power of pharmacogenomics (PGx) panel testing PGx aims to understand how individual genetic differences influence drug response, enabling personalized medicine research. While several amplicon studies have shown the…