Blog
July 22, 2013
Whole-Genome Microbial Epigenetics: ASM Workshop videos highlight emerging application of SMRT Sequencing
We recently participated in a workshop on whole-genome microbial epigenetics at the American Society for Microbiology annual meeting in Denver. Using SMRT® Sequencing, the three most common types of bacterial…
July 10, 2013
University of Oslo Scientists Use Long Reads for Unique Look at Cod Genome
Scientists at the University of Oslo’s Centre for Ecological and Evolutionary Synthesis (CEES) have used multi-kilobase sequence reads from the PacBio® RS sequencer to produce a dramatically improved genome assembly…
July 3, 2013
Genome Biology Commentary Discusses the Advantages of SMRT Sequencing
A new commentary in Genome Biology from highly respected scientific authors, including a Nobel Prize winner, highlights the benefits of Single Molecule, Real-Time (SMRT®) Sequencing. The commentary, entitled “The advantages…
July 3, 2013
Using PacBio Sequencing, Scientists Find No Evidence of Horizontal Gene Transfer in Haitian Cholera Strain
A new analysis from public health scientists has found that the cholera strain responsible for the 2010 outbreak in Haiti has a limited ability to add to its genetic repertoire…
June 18, 2013
Back from SFAF, and Eager for More Finished Genomes
Last month’s Sequencing, Finishing, Analysis in the Future (SFAF) meeting in Santa Fe, New Mexico, hosted by Los Alamos National Laboratory, attracted terrific scientists and we really enjoyed hearing about…
June 14, 2013
Two Worlds of Genome Assemblers
by Jonas Korlach, Chief Scientific Officer Finished genomes were the focus of last month’s Sequencing, Finishing, Analysis in the Future (SFAF) meeting in Santa Fe, New Mexico. In addition to…
June 4, 2013
Jonas Korlach Honored by White House as an Immigrant ‘Champion of Change’
Last week the White House held an event to honor eleven Immigrant Innovator “Champions of Change” — the best and brightest from around the world who are helping create American…
May 14, 2013
Nature Methods Paper Demonstrates a Cost-Effective Process for Finishing Genomes
A paper recently published in Nature Methods offers a deep dive into the use of our HGAP and Quiver tools to generate a high-quality genome assembly with an automated, simplified…
April 29, 2013
PNAS: Copy Number Analysis in Maize Sheds Light on Tolerance for Acidic Soil
A new study of maize sheds light on the importance of copy-number variation in genes related to stress tolerance with implications to boost crop yield in suboptimal soil environments. A…
April 23, 2013
Current Opinion in Microbiology: Bacterial Methylomes in Review – ‘An Exciting Era’
A new review paper from Brigid Davis, Michael Chao, and Matthew Waldor at Harvard Medical School considers a number of recent studies and findings that have used single molecule, real-time…
April 18, 2013
Guest Blog: Michael Schatz shares his perspective on the new PacBio RS II
Michael Schatz, Ph.D. Assistant Professor of Quantitative Biology at Cold Spring Harbor Laboratory, shares some thoughts about his experience with the PacBio RS and his hopes for future work with…
April 10, 2013
Rapid Genome Assembly: Salmonella Outbreak Strain Sequenced and Closed in Less Than One Week
A newly reported Salmonella genome showcases the utility of single molecule, real-time (SMRT®) sequencing for characterizing a foodborne outbreak pathogen. The outbreak strain, Salmonella enterica subsp. enterica serovar Javiana (S….
April 9, 2013
It’s a Very Microbial Season
This springtime, we’ve got microbes on the brain! The annual meeting of the American Society for Microbiology is just over a month away, so we’ve been thinking a lot about…
March 20, 2013
Want to Try Out the PacBio RS? Our Sequencing Providers Can Help
It has been really gratifying to see that interest in Single Molecule, Real-Time (SMRT®) Sequencing has been steadily increasing — there seems to be lots of pent-up demand to run…
March 18, 2013
Sequencing Innovations Offer a More Complete Picture for Microbes
We’re pleased to share with you a recent article from Microbe magazine, a publication of the American Society for Microbiology, from Eric Schadt, founding director of the Icahn Institute for…