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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

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SMRT Sequencing Offers First Look at Fragile X Syndrome Repeat Expansion Disorder Sequence

Scientists at the University of California, Davis, School of Medicine have used the PacBio® RS to sequence a previously “unsequenceable” region of highly repetitive DNA on the X chromosome, providing…

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PAG Highlights and Workshop Recording: Generating High-Quality Bacterial, Plant and Animal Genomes

It was great to visit sunny San Diego for the International Plant and Animal Genome meeting last month. We were impressed with the quality of talks and posters, and we…

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Genome Finishing Gets Easier with PacBio Software Update

Plus: Accuracy Boost, Integrated Full-Length cDNA Analysis and Barcoding Support We’re pleased to announce the release of a new software upgrade — SMRT® Analysis v1.4.0 — that achieves higher quality…

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SMRT Sequencing for Industrial Biotech Applications

A feature article in the December 2012 issue of Industrial Biotechnology reports on various case studies where scientists have used the unique capabilities of SMRT® Sequencing to make discoveries in…

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A Closer Look at Accuracy in PacBio Sequencing

By Jonas Korlach, Chief Scientific Officer Single Molecule, Real-Time (SMRT®) DNA sequencing achieves highly accurate sequencing results, exceeding 99.999% (Q50) accuracy, regardless of the DNA’s sequence context or GC content….

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SMRT sequencing selected by 100K Pathogen Genome Project to finish genomes

A recently announced partnership with the University of California, Davis (UC Davis) highlights the benefits of one of the key applications for Single Molecule, Real-Time (SMRT®) Sequencing: rapid and complete…

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Baylor Team Uses PacBio’s SMRT® Sequencing to Upgrade and Finish Draft Genomes

Scientists at the Human Genome Sequencing Center at Baylor College of Medicine recently published a paper demonstrating the utility of PacBio’s long reads for upgrading and finishing draft genomes. “Mind…

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PAG 2013 – What Would You Do with a Complete Genome?

We’re pleased to be hosting a workshop at the 21st annual International Plant & Animal Genome conference in San Diego next week — and whether you’re attending or not, we…

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Looking Ahead: The 2013 PacBio Technology Roadmap

By Jonas Korlach, Chief Scientific Officer With our minds turning to what 2013 has in store for us, it’s a good opportunity to look ahead to the advances you can…

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