Blog
February 21, 2013
AGBT Day 1 Highlights: Focus on Epigenetics
Years ago, “epigenetics” was largely synonymous with methylation — in particular, 5-methylcytosine, which could be analyzed through bisulfite sequencing. Today, technologies have advanced and so has our understanding of the…
February 20, 2013
AGBT 2013: Meeting Preview & PacBio Activities
This week we are fortunate to be attending the annual Advances in Genome Biology & Technology (AGBT) meeting in Marco Island, FL. The conference is always jam-packed with top tier…
February 14, 2013
Mendelspod Interview with Mike Hunkapiller, CEO of Pacific Biosciences
Mike Hunkapiller was interviewed for a podcast recently on Mendelspod. In it, Mike and Mendelspod host Theral Timpson chat about the current sequencing technology landscape, clinical applications of sequencing, and…
February 11, 2013
SMRT Sequencing Offers First Look at Fragile X Syndrome Repeat Expansion Disorder Sequence
Scientists at the University of California, Davis, School of Medicine have used the PacBio® RS to sequence a previously “unsequenceable” region of highly repetitive DNA on the X chromosome, providing…
February 7, 2013
PAG Highlights and Workshop Recording: Generating High-Quality Bacterial, Plant and Animal Genomes
It was great to visit sunny San Diego for the International Plant and Animal Genome meeting last month. We were impressed with the quality of talks and posters, and we…
January 31, 2013
Genome Finishing Gets Easier with PacBio Software Update
Plus: Accuracy Boost, Integrated Full-Length cDNA Analysis and Barcoding Support We’re pleased to announce the release of a new software upgrade — SMRT® Analysis v1.4.0 — that achieves higher quality…
January 31, 2013
SMRT Sequencing for Industrial Biotech Applications
A feature article in the December 2012 issue of Industrial Biotechnology reports on various case studies where scientists have used the unique capabilities of SMRT® Sequencing to make discoveries in…
January 22, 2013
A Closer Look at Accuracy in PacBio Sequencing
By Jonas Korlach, Chief Scientific Officer Single Molecule, Real-Time (SMRT®) DNA sequencing achieves highly accurate sequencing results, exceeding 99.999% (Q50) accuracy, regardless of the DNA’s sequence context or GC content….
January 17, 2013
SMRT sequencing selected by 100K Pathogen Genome Project to finish genomes
A recently announced partnership with the University of California, Davis (UC Davis) highlights the benefits of one of the key applications for Single Molecule, Real-Time (SMRT®) Sequencing: rapid and complete…
January 14, 2013
Baylor Team Uses PacBio’s SMRT® Sequencing to Upgrade and Finish Draft Genomes
Scientists at the Human Genome Sequencing Center at Baylor College of Medicine recently published a paper demonstrating the utility of PacBio’s long reads for upgrading and finishing draft genomes. “Mind…
January 11, 2013
PAG 2013 – What Would You Do with a Complete Genome?
We’re pleased to be hosting a workshop at the 21st annual International Plant & Animal Genome conference in San Diego next week — and whether you’re attending or not, we…
January 9, 2013
Looking Ahead: The 2013 PacBio Technology Roadmap
By Jonas Korlach, Chief Scientific Officer With our minds turning to what 2013 has in store for us, it’s a good opportunity to look ahead to the advances you can…