Blog
September 17, 2015
SMRT Data Analysis: Updates from our Developers Conference
Last month we hosted a SMRT® Informatics Developers Conference, bringing together 150 developers with a passion for improving tools and resources. Our team came back brimming with enthusiasm for tools…
September 8, 2015
Webinar: Long Fragment Capture for SMRT Sequencing
Roche recently posted this recording of a webinar walking through long fragment capture with SMRT® Sequencing. “Long Genomic DNA Fragment Capture and SMRT Sequencing Enables Accurate Phasing of Cancer and…
August 26, 2015
In Bacterial Study, Scientists Link Epigenetic Switch to Virulence, Antibiotic Resistance, and More
Scientists from Griffith University, Ohio State University College of Medicine, and other institutions recently published a detailed study of phase-variable expression of a DNA methyltransferase in non-typeable Haemophilus influenzae, the…
August 20, 2015
The Gapless Assembly: Scientists Describe Workflow for Producing Complete Eukaryote Genome
Sunflowers with verticillium wilt caused by V. dahliae In a new mBio publication, scientists from Wageningen University and KeyGene in The Netherlands report results from several strategies used to assemble…
August 12, 2015
Using SMRT Sequencing, Scientists Uncover Unexpected Transcript Diversity in Fungi
A new PLoS One publication from scientists at the Joint Genome Institute, University of Minnesota, and other organizations demonstrates that fungal genomes may contain far more transcript diversity than previously…
July 23, 2015
SMRT Sequencing Provides Novel View of Long-Term Viral Evolution in a Single Patient
A group of scientists from the University of Pittsburgh School of Medicine and New York University used long-read sequencing from PacBio for a remarkable new study characterizing influenza virus evolution…
July 21, 2015
Webinar: Anthony Nolan’s Neema Mayor Reports on HLA Typing with Long Reads
Following the recent paper about HLA typing from scientists at Anthony Nolan Research Institute, we thought readers might enjoy this webinar from Neema Mayor, a scientist at the institute and…
July 14, 2015
SMRT Sequencing Contributes to Detection of DNA Methylation in C. elegans
A recent paper in the journal Cell presents novel findings of DNA methylation in C. elegans, an organism previously believed not to have such epigenetic marks. Scientists used several approaches…
July 9, 2015
The Festival of Genomics Review: A Celebration of Long Reads
At the inaugural Festival of Genomics event in Boston, more than 1,500 people turned out to see what was billed as a conference unlike any other. The meeting was indeed…
June 29, 2015
Nature Methods Paper Uses Long-Read Data for Highly Contiguous Diploid Human Genome
A new publication in Nature Methods describes a new single-molecule assembly approach that resulted in “the most contiguous clone-free human genome assembly to date,” according to lead authors Matthew Pendleton,…
June 25, 2015
SMRT Data Delivers for Next-Generation HLA Typing at Anthony Nolan Research Institute
A new publication in PLoS One from authors at Anthony Nolan’s Research Institute describes a feasibility study for HLA typing using SMRT® Sequencing. The research institute, where the world’s first…
June 15, 2015
Scientists Publish New Methylation Analysis Protocols Using SMRT Sequencing
Scientists from the Icahn School of Medicine at Mount Sinai and the University of Saskatchewan teamed up to develop an innovative approach to methylation analysis using Single Molecule, Real-Time (SMRT®)…
June 11, 2015
Updated! Data Release: Human MCF-7 Transcriptome
UPDATE: Our R&D team has added a new dataset for the MCF-7 human breast cancer transcriptome, originally released in 2013. The new results were produced using 28 SMRT® Cells with…
June 9, 2015
Attend Our Worldwide User Meetings & SMRT Informatics Developers Conference
If you’d like to hear about the latest applications of SMRT® Sequencing from users, we have several events coming up. Our worldwide user group meetings and workshops feature PacBio users…
June 2, 2015
In Assembler Evaluation, Scientists Recommend Non-hybrid Approach to Bacterial Genomes
A new publication in Nature Scientific Reports recommends using only the PacBio® system to sequence bacterial genomes for the best chance of generating an accurate and finished assembly. The paper,…