Blog
October 5, 2015
Beyond the $1,000 Genome: An Interview with Mark Gerstein
Next-generation sequencing has many people excited about the prospect of the $1,000 genome, however recent discoveries show that short-read sequencing technologies miss important genomic elements, driving scientists to look for…
October 2, 2015
Toward Platinum Genomes: PacBio Releases a New, Higher-Quality CHM1 Assembly to NCBI
As part of our effort to support the National Institutes of Health and the Genome Reference Consortium (GRC) in creating platinum genomes for the research community and improving the reference…
October 1, 2015
ASHG 2015: Workshop, Presentations, and First Chance to See the Sequel System
We’re looking forward to the year’s biggest scientific meeting focused on human genetics next week — the American Society of Human Genetics (ASHG) 2015 annual meeting, taking place in Baltimore,…
September 30, 2015
Introducing the Sequel System: The Scalable Platform for SMRT Sequencing
We are excited to announce our newest Single Molecule, Real-Time sequencer, the Sequel™ System. Watch this short video to learn about this exciting evolution in SMRT® Sequencing. The Sequel System…
September 25, 2015
Marc Salit at NIST: Defining Standards for the Human Genome
In the first podcast of a new series on the applications of long-read sequencing, Mendelspod host Theral Timpson interviewed Marc Salit, leader of the Genome Scale Measurements Group at the…
September 24, 2015
At Genome in a Bottle Workshop, Progress on New Reference Materials
Genome in a Bottle consortium The National Institute of Standards and Technology held its latest Genome in a Bottle workshop last month in Gaithersburg, Md., and we were honored to…
September 23, 2015
SMRTest Microbe Grant Winner: Identifying Antibiotic Resistance Mechanisms with SMRT Sequencing
We’re pleased to announce the winner of our recent “SMRTest Microbe” grant competition. Congratulations to Dr. Erin Price at the Menzies School of Health Research in Australia! The grant program,…
September 17, 2015
SMRT Data Analysis: Updates from our Developers Conference
Last month we hosted a SMRT® Informatics Developers Conference, bringing together 150 developers with a passion for improving tools and resources. Our team came back brimming with enthusiasm for tools…
September 8, 2015
Webinar: Long Fragment Capture for SMRT Sequencing
Roche recently posted this recording of a webinar walking through long fragment capture with SMRT® Sequencing. “Long Genomic DNA Fragment Capture and SMRT Sequencing Enables Accurate Phasing of Cancer and…
August 26, 2015
In Bacterial Study, Scientists Link Epigenetic Switch to Virulence, Antibiotic Resistance, and More
Scientists from Griffith University, Ohio State University College of Medicine, and other institutions recently published a detailed study of phase-variable expression of a DNA methyltransferase in non-typeable Haemophilus influenzae, the…
August 20, 2015
The Gapless Assembly: Scientists Describe Workflow for Producing Complete Eukaryote Genome
Sunflowers with verticillium wilt caused by V. dahliae In a new mBio publication, scientists from Wageningen University and KeyGene in The Netherlands report results from several strategies used to assemble…
August 12, 2015
Using SMRT Sequencing, Scientists Uncover Unexpected Transcript Diversity in Fungi
A new PLoS One publication from scientists at the Joint Genome Institute, University of Minnesota, and other organizations demonstrates that fungal genomes may contain far more transcript diversity than previously…
July 23, 2015
SMRT Sequencing Provides Novel View of Long-Term Viral Evolution in a Single Patient
A group of scientists from the University of Pittsburgh School of Medicine and New York University used long-read sequencing from PacBio for a remarkable new study characterizing influenza virus evolution…
July 21, 2015
Webinar: Anthony Nolan’s Neema Mayor Reports on HLA Typing with Long Reads
Following the recent paper about HLA typing from scientists at Anthony Nolan Research Institute, we thought readers might enjoy this webinar from Neema Mayor, a scientist at the institute and…
July 14, 2015
SMRT Sequencing Contributes to Detection of DNA Methylation in C. elegans
A recent paper in the journal Cell presents novel findings of DNA methylation in C. elegans, an organism previously believed not to have such epigenetic marks. Scientists used several approaches…