Blog
November 7, 2018
Fishing for Human-Specific Isoforms
When scientists want to investigate human-specific evolution, the best place to start is often with a comparison to our closest cousins, the great apes. Some recent high-quality PacBio genome assemblies…
November 5, 2018
SMRT Grant Winner: Preventing Infection for Premmies
We’re pleased to announce the winner of the 2018 Microbial Genomics SMRT Grant. Mark Webber, Research Leader at Quadram Institute Bioscience in the UK, will get free SMRT Sequencing and…
November 1, 2018
Genetic Code of All Plants, Animals, Protozoa, and Fungi to be Sequenced with Help of PacBio
It’s one of the most ambitious sequencing projects ever attempted — the assembly of all 1.5 million known species of animals, plants, protozoa and fungi on Earth — and SMRT…
October 31, 2018
Smell of Success: Garlic Study Validates New Approach to Transcriptome Association
Genome-wide association studies (GWAS) may be powerful tools for the identification of genes underlying complex traits, but what if you have an incredibly complex, uncharacterized genome, with no sequenced progenitor…
October 22, 2018
SMRT Sequencing and a Bit of Luck Help Swiss Microbiologists Solve Decades-Old Mystery
It’s a murder mystery of massive proportion, albeit on a miniature scale: Male-killing among several species of insects, caused by selfish symbiotic bacteria. Swiss researchers believe they have finally solved…
October 10, 2018
Sequel System 6.0 Release Offers a New Paradigm in DNA Sequencing: Highly Accurate Single-Molecule Long Reads
Today we’re pleased to announce the release of Sequel System 6.0, including new software, consumable reagents and a new SMRT Cell. Combined, the enhancements in the release improve the performance and affordability of…
October 8, 2018
Data Release: Highest-Quality, Most Contiguous Individual Human Genome Assembly to Date
We’re proud to announce the release of the most contiguous diploid human genome assembly of a single individual to date, representing the nearly complete DNA sequence from all 46 chromosomes…
October 4, 2018
Sanger Institute Birthday Gift to Scientists: 25 New Wildlife Genomes to Support Conservation and Science
King scallops are more genetically diverse than we are? The Roesel’s bush cricket’s genome is four times the size of ours? These are just some of the findings made by…
October 3, 2018
Beloved Barn Swallow Gets SMRT Sequencing “Platinum Genome” Treatment
UPDATED Dec. 3, 2018 Congratulations to the Italian team on the publication of their European barn swallow genome! The paper is now available at GigaScience. ORIGINAL POST Oct. 3, 2018 With…
September 25, 2018
Iso-Seq SMRT Grant Winner to Study Alternative Splicing in Neurons
Xiaochang Zhang, an assistant professor at the University of Chicago, is poised to get a powerful new data set to help his team understand the role of alternative splicing in…
September 18, 2018
Must-Have PacBio Applications & Services: Getting the Most from SMRT Sequencing
In addition to the most common applications, like whole genome sequencing for de novo assembly, there are several other features you can utilize to advance your science or incorporate to…
September 13, 2018
Building a Digital Genome Ark: Vertebrate Genome Project Releases 15 New Reference Genomes
When creating a global genomic ark of creatures great and small, scientists are turning to the comprehensive coverage and quality of PacBio sequencing. The Vertebrate Genomes Project (VGP), an international…
September 12, 2018
How to Incorporate New Features into Your Sequencing Services Menu
Many people who run a sequencing core lab would prefer to focus on science instead of business, but all core lab managers know that it’s imperative to keep a steady…
September 6, 2018
New Look at Breast Cancer Cell Line Sheds Light on Structural Complexity
In an exciting paper that made the cover of Genome Research, scientists from Cold Spring Harbor Laboratory and collaborating institutions report the genome sequence and transcriptome of a commonly used…
September 4, 2018
Webinar Summary: Developing Benchmark Sets for Structural Variants
A map of every individual’s genome will soon be possible, but how will we know if it is correct? Benchmarks are needed in order to check the performance of sequencing,…