Blog
September 13, 2018
Building a Digital Genome Ark: Vertebrate Genome Project Releases 15 New Reference Genomes
When creating a global genomic ark of creatures great and small, scientists are turning to the comprehensive coverage and quality of PacBio sequencing. The Vertebrate Genomes Project (VGP), an international…
September 12, 2018
How to Incorporate New Features into Your Sequencing Services Menu
Many people who run a sequencing core lab would prefer to focus on science instead of business, but all core lab managers know that it’s imperative to keep a steady…
September 6, 2018
New Look at Breast Cancer Cell Line Sheds Light on Structural Complexity
In an exciting paper that made the cover of Genome Research, scientists from Cold Spring Harbor Laboratory and collaborating institutions report the genome sequence and transcriptome of a commonly used…
September 4, 2018
Webinar Summary: Developing Benchmark Sets for Structural Variants
A map of every individual’s genome will soon be possible, but how will we know if it is correct? Benchmarks are needed in order to check the performance of sequencing,…
August 31, 2018
International Eagle Conservation Efforts Bolstered By New Genome Release
Genetics is not only key to discovering and tracing new traits in an organism, but also conserving old ones — and in some cases, the species itself. A deep understanding…
August 7, 2018
PacBio Sequencing Reveals Food Processing & Pathogenic Strains of Yeast are the Same Species
What’s in a name? Too much, when it comes to the taxology of yeast, it turns out. Scientists from University College of Dublin have found that two distinctly named species…
August 1, 2018
Something to Crow About: SMRT Sequencing Aids Conservation of Rare Hawaiian Bird
Brought to the brink of extinction, the future of Hawaii’s only lineage of the crow family (Corvidae) is looking up thanks to intensive conservation genomics efforts using PacBio de novo…
July 30, 2018
Diversity of Unexpected CRISPR Edits Revealed by SMRT Sequencing
A new Nature Biotechnology publication is sending reverberations through the CRISPR and gene therapy communities. The discovery that the widely used CRISPR/Cas9 method results in far more genomic changes than…
July 27, 2018
Deep Dives into DNA of Marine Biology
“Live every week like it’s Shark Week,” 30 Rock character Tracy Jordan once quipped to Kenneth the Page, referencing the week-long, dorsal-finned programming phenomenon that has become the Discovery Channel…
July 24, 2018
SMRT Science, Tips & Tricks Presented at Leiden Meeting
When was the last time you sent your DNA off to a day at the spa? Olga Pettersson of the SciLifeLab at Uppsala University lets her molecules relax for up…
July 17, 2018
Long Look Into Ant Brains Provides Epigenetic Insights
To understand the epigenetic regulation of brain function and behavior, scientists are turning to ants. To understand the ants, they are applying the accurate, long reads of SMRT Sequencing. While…
July 13, 2018
Egyptian Rousette Bat Genome Provides Clues to Antiviral Mystery
When humans are infected with the Marburg virus, the result is often lethal, with hemorrhagic fever and other symptoms similar to Ebola. When bats are infected, the result is…. nothing….
July 11, 2018
Maize Collaborators Embark on Ambitious 26-line Pangenome Project
The first reference genome for maize variety B73, completed in 2009, was a major milestone, and an improved version released by Cold Spring Harbor Laboratory scientists in 2017 provided a…
July 10, 2018
One Million Genomes Meeting Discusses Progress and Promise of Population-Scale Genomics
The PacBio team was honored to attend an excellent Keystone Symposium in Hannover, Germany recently. The event, “One Million Genomes: From Discovery to Health,” offered a rare look at…
June 27, 2018
Plant and Animal SMRT Grant Will Enable Insight Into Sightless Fish
When German diver Joachim Kreiselmaier reached the deepest parts of the Danube-Aach cave system, he couldn’t believe his eyes: a “strange fish,” with a pale body coloration and smaller eyes…