Video Gallery

Learn how HiFi reads are empowering leading core labs and service providers, and how the new Sequel IIe System, which directly outputs HiFi reads, is making it easier than ever before to get started with HiFi reads or add capacity.

In this video Jonas Korlach, PacBio Chief Scientific Officer, shares how PacBio is partnering with LabCorp to use highly accurate long-read sequencing in support of global efforts for genome surveillance of SARS-CoV-2. Dr. Korlach describes the benefits of the HiFiViral for SARS-CoV-2 Workflow for delivering complete viral genomes as well as variant detection successes made to date using the workflow. Learn more about the HiFiViral for SARS-CoV-2 Workflow at https://pacb.com/COVID-19

In this video, Dave Miller from PacBio and Alvaro Hernandez PhD from the University of Illinois Urbana- Champaign discuss how to create Core Lab demand using PacBio highly accurate long-read, or HiFi, sequencing.

In this talk, Aaron Wenger from PacBio uses industry examples to describe how using highly accurate long-reads, or HiFi reads, provides the most comprehensive result, giving you greater than 99.9% accuracy, up to 25 kb long.

PacBio Sequencing and software enable the generation of highly accurate (>99.9%) long reads. HiFi reads are accurate, essential, affordable, and can be used across a range of applications, including detection of all variant types, from single nucleotides to structural variants. PacBio’s end-to-end solutions feature library preparation paired with push-button analysis to support numerous workflows so you can run projects quickly and easily.

In this panel discussion, service providers share their experiences in bringing PacBio Systems to their labs, from the purchasing process, through managing demand for instrument time, and describe how PacBio solutions offer customers the most informative data available.

In this talk, Jonas Korlach, PhD, Chief Scientific Officer at PacBio describes how using PacBio HiFi reads, which are greater than 99.9% accurate and up to 25 kb long, led to the detection of structural variants in examples of previously unexplained rare genetic diseases. Genetic diseases affect as much as 10% of the population and over 50% of cases currently remain unexplained. Similarly, Mendelian diseases include over 8,500 described disorders, however at present ~40% have an unknown genetic cause. In addition, he highlights the strength of complete, phased, high-accuracy human WGS for simultaneously yielding high-quality information about any other locus or group of loci, which results in a single genetic assay that encompasses all others.

In this webinar, hear from Jeanette Gehrig, Ph.D., Senior Scientist at Siolta Therapeutics, about how her team is leveraging PacBio metagenomic sequencing to achieve: (1) Strain-level resolution of bacteria from fecal samples, (2) More functional profiling information with less sequencing data, and (3) Multiple single contig MAGs from fecal samples, multiplexed at 3 samples per SMRT Cell 8M. She also shares real world examples, including data from a retrospective clinical trial for a live biotherapeutic product.

In this PAGBioDay 2021 presentation, Michelle Vierra of PacBio provides the official welcome to PAGBio Day including a presentation on the latest in HiFi sequencing. Michelle is be followed by a keynote presentation by Harris Lewin, Chair of the Earth BioGenome Project at UC Davis, who shares updates and new insights drawn from global conservation initiatives.

In this PAGBio Day 2021 presentation, Bo Wang of Cold Harbor Spring Laboratory shares his work constructing chromosome-level genome assemblies for two sorghum inbred lines using long-read sequencing leading to the first overview of the extent of genomic structural variations, and potential targets for sugarcane aphid resistance breeding.