Blog
April 18, 2016
First Comprehensive Analysis of Mosquito Y Chromosome Offers Clues for Vector Control
A new PNAS paper offers the first detailed analysis of the Anopheles gambiae Y chromosome, which could prove critical for biological and infectious disease research. The report uncovered extensive remodeling…
April 15, 2016
Japanese Scientists Find Gene Fusion Driving B Cell Leukemia
In a new Nature Genetics paper, scientists from the University of Tokyo and several other Japanese institutes and hospitals present results of a sweeping study of gene fusions driving a…
April 14, 2016
Accelerating Cancer Research Discovery with SMRT Sequencing at AACR 2016
The PacBio team is gearing up for the annual meeting of the American Association for Cancer Research (AACR), which will be held April 16-20 in New Orleans. We’re looking forward…
April 13, 2016
Genome and Transcriptome Analysis Help Scientists Deconstruct Cancer Complexity
At Cold Spring Harbor Laboratory, scientists used SMRT® Sequencing to decode one of the most challenging cancer genomes ever encountered. Along the way, they built a portfolio of open-access analysis…
April 11, 2016
From Earthworms to Alpacas: Vote Now to Choose the Next SMRT Grant Program Winner!
For the first time ever, the winner of this year’s “Explore Your Most Interesting Genome” SMRT Grant program will be decided by the community. We’ll be using our new Genome…
March 31, 2016
With Greater Contiguity, New Gorilla Genome Assembly Offers Insights into Gene Content, SVs, and More
In a Science paper published today, scientists from the University of Washington, the McDonnell Genome Institute, and other organizations present a new gorilla genome assembly generated with PacBio long-read sequencing,…
March 30, 2016
New Study Uses SMRT-ChIP Method to Find Novel Methylation in Mouse Embryonic Stem Cells
In a new Nature publication, scientists from Yale and other institutions report the discovery of N6-methyladenine (N6-mA) in mouse embryonic stem cells (ESCs), contrary to the conventional wisdom that the…
March 24, 2016
CSHL Scientists Discuss Long-Read Sequencing for More Contiguous Assemblies and Complex Genomes
Much like the “sharpen” tool in Photoshop brings a picture into tighter focus and enhances the fine detail, long-read sequencing offers enhanced resolution of genomic information, according to Cold Spring…
March 15, 2016
Genome Galaxy Initiative:
On a Mission to Sequence the Beautiful and Mysterious Kākāpō
New Zealand is more than an amazing vacation destination or the setting of the Lord of the Rings movies; it’s also home to a wealth of fascinating species that evolved…
March 3, 2016
Prevalent Methylation in Prokaryotic Genomes Suggests Regulatory Functions
A new publication from scientists at Lawrence Berkeley National Laboratory, the Joint Genome Institute, and other organizations reports a landmark study of genome-wide methylation in prokaryotes. The analyses of 230…
February 29, 2016
On Rare Disease Day, celebrating the contributions of genomics
Today we are celebrating Rare Disease Day with like-minded folks all over the world. The tribute kicked off in 2008 and has gathered so much momentum that people in more…
February 25, 2016
New Views of Microbial Communities Call for Updates to Infectious Disease Tenets
In a perspective recently published in Science magazine, scientists Allyson Byrd and Julie Segre from the National Human Genome Research Institute used recent advances in microbial analysis to look at…
February 23, 2016
15th Anniversary of the Human Genome Publication; A Conversation with Mike Hunkapiller
This month serves as the 15th anniversary of the first publication of the human genome by both public and private efforts. PacBio CEO Mike Hunkapiller was a central player in…
February 22, 2016
AGBT Day 4: A Better Gorilla Assembly, and Data from the Sequel System
On the final day of AGBT, attendees strapped in for the last talks of the conference before the ’80s-themed dance party to close out the meeting. Two of those talks focused on…
February 19, 2016
AGBT Day 3: Human Genomes and Their Microbial Friends
We’ve been in the genomics world long enough to remember when it was a big deal to see a great single-gene assembly or microbial genome assembly reported in an AGBT…