Blog
June 12, 2017
Scientists Use SMRT Sequencing to Reveal Unexpected Adhesin Repertoire in Candida
In a preprint available from bioRxiv, scientists from the University of Lausanne and Swiss Institute of Bioinformatics present the first SMRT Sequencing results from isolates of the fungal pathogen Candida…
June 8, 2017
Widespread Methylation in Earliest Fungi Offers Clue to Expression of Essential Genes
The Joint Genome Institute recently announced results from a project that used SMRT Sequencing to generate high-quality genome assemblies and detect epigenetic modifications for fungal species that represent the earliest…
June 6, 2017
At CROPS 2017, SMRT Sequencing Powers Reference Plant Genome Assemblies
This week the HudsonAlpha Institute for Biotechnology and the University of Georgia are co-hosting CROPS 2017, a meeting focused on genomic technologies and their use in crop improvement and breeding…
June 2, 2017
In Texas, New View of Klebsiella Strain Diversity and Antibiotic Resistance
A sweeping new report on Klebsiella pneumoniae sequence data from scientists at the Houston Methodist Research Institute, Weill Cornell Medical College, and other institutions found more diversity than expected in strains…
May 30, 2017
At ASM Microbe 2017, SMRT Sequencing Advances Microbial Applications
We can’t wait for ASM Microbe! It’s one of the largest microbiology conferences in the world and is taking place June 1-5 in New Orleans. With more than 10,000 people…
May 24, 2017
Genome Assembly Advances Featured in Genome Research Special Issue
The May issue of Genome Research is a special edition focusing on advances in sequencing technologies and genome assembly techniques. The research papers selected for this special issue cover reference-grade…
May 18, 2017
TB Study Finds Some Previously Reported Virulence Variants Were Sequencing Errors
A publication in BMC Genomics upends some of the conventional wisdom about variants that may cause virulence in Mycobacterium tuberculosis. Scientists at San Diego State University used SMRT Sequencing to…
May 2, 2017
New Iso-Seq Chicken Analysis Finds Missing Genes and Transcript Complexity
A new publication in BMC Genomics explores the use of RNA normalization and 5’ cap selection to enhance results from Iso-Seq studies using SMRT Sequencing. Scientists from the University of…
May 1, 2017
SMRT Sequencing Enables Accurate Calling of Pathogenic Variants in Medically Relevant Genes
Screening for pathogenic variants associated with polycystic kidney disease is now more accurate and affordable with SMRT Sequencing. A new paper in Human Mutation from scientists at Leiden University Medical…
April 25, 2017
Happy DNA Day! A Celebration of Great Science
It’s DNA Day, the annual celebration of the discovery of the double helix, the completion of the Human Genome Project, and all things genetic. We like to take the opportunity…
April 22, 2017
On Earth Day, a Shout Out to the Conservation Genomics Community
Today is Earth Day, a great time to reflect on the growing trend of conversation genomics. We are proud that many scientists are using PacBio long-read sequencing for the goal…
April 21, 2017
Review Paper Showcases Clinical Applications for SMRT Sequencing
Researchers from the Okinawa Institute of Advanced Sciences published a compelling review article describing several recent clinically relevant projects they have completed using SMRT Sequencing. Released in the journal Human…
April 13, 2017
New QC pipeline for Iso-Seq data increases confidence in transcript results
A preprint from scientists at the University of Florida, Centro de Investigaciones Principe Felipe, and other institutes describes a new analysis tool to help boost quality of transcriptome studies. “SQANTI:…
April 11, 2017
Crow Genome Analysis Combines Assemblies to Spot Tandem Arrays
A new publication in Genome Research shows how the use of SMRT Sequencing, in combination with other technologies, can reveal far more about repetitive DNA and structural variants than short-read…
April 10, 2017
Network with the SMRT Community at Our Upcoming User Group Meetings & Events
We are excited to announce our 2017 series of SMRT Community Events and User Group Meetings (UGMs), where you can learn first-hand how members of the scientific community are leveraging…