Blog
April 17, 2018
Scientists Aim to Develop “Genomic Ark” of High-Quality Bat Genomes
Pop quiz: Which animal accounts for around 20% of all living mammals, harbors (yet survives) some of the world’s deadliest diseases, lives proportionately longer than humans given its body size,…
April 12, 2018
SMRT Sequencing Enables Characterization of Cavities-Causing Bacteria in Children
We’re told to avoid sugar and refined carbohydrates if we want our teeth to remain strong and cavity-free. But what is the role of microbiota in our oral health? Cavities…
April 11, 2018
HudsonAlpha Chooses Sequel System for NIH-Funded Program Focused on Challenging Pediatric Cases
At the HudsonAlpha Institute for Biotechnology, scientists are building on advances in agricultural research to power a clinical pediatric research program. For this work, they’re using the Sequel System to…
April 9, 2018
Rice Revelations: Nine New Genome Assemblies Uncover Key Traits and Evolutionary Clues
Revered around the world, rice is a staple food for nearly half of the population. But as that population grows, rice breeders are faced with the challenge of producing crops…
April 5, 2018
New M. Oryzae Assembly Reveals Importance of Previously Missed Transposable Elements
A publication from the Molecular Plant journal demonstrates the use of SMRT Sequencing to characterize activity of transposable elements in Magnaporthe oryzae, the destructive fungus responsible for rice blast disease….
April 2, 2018
Disease-Causing Mobile Element Identified with SMRT Sequencing, Validated with CRISPR
In an exciting new Cell paper, scientists report identification of an intronic structural variant that causes a neurodegenerative Mendelian disorder that primarily affects people on the island of Panay in…
March 28, 2018
Bio-IT World: Genomic Data Standards Are a ‘Necessity’
Genomic data standards will be essential for continuing the growth of genomics and ensuring its smooth transition into the clinic, according to a new Bio-IT World article written by PacBio…
March 20, 2018
New cattle genome overcomes challenges of haplotype assembly
Genetic knowledge is powerful when it comes to breeding. The ability to trace desirable traits to the gene level can help create plants and animals that are adapted to existing…
March 19, 2018
New High-Quality Swedish Genome Assemblies Identify Novel Population-Specific Reference Sequence
UPDATE: This paper has now been published in Genes. A new preprint from scientists at Uppsala University’s SciLifeLab reports the de novo genome sequencing and assembly of two Swedish individuals…
March 15, 2018
Study: SMRT sequencing can improve the safety of gene therapy protocols
A new publication in the journal of the American Society of Gene & Cell Therapy demonstrates the novel use of SMRT Sequencing for improving the safety and quality of a…
March 12, 2018
A new look at an old favorite: Cabernet Sauvignon study generates a transcriptome of ripening berries
UPDATE: The study has been published in the journal G3: GENES, GENOMES, GENETICS and featured on its cover. ORIGINAL POST (March 12, 2018): A new preprint from scientists at the…
March 9, 2018
Coral Microbiome Project Wins 2017 Microbial SMRT Grant
Corals are critical to sustaining sea life in many parts of the world, contributing to an elaborate ecosystem that lives in and around their mineralized calcium carbonate skeletons. In addition…
March 7, 2018
New Software, Polymerase for Sequel System Boost Throughput and Affordability
Today we’re pleased to announce the release of a new version of Sequel Software (V5.1) and a new polymerase. Combined, these upgrades increase throughput and overall performance for key SMRT…
March 5, 2018
Dog meet dog world: Exploring canine genomes
UPDATE (October 2020): Sandy’s genome assembly is now available here. From wild animals to perfect pets, dogs have undergone some interesting changes during their centuries-long domestication. Intent on unraveling some…
February 28, 2018
Join us in recognizing Rare Disease Day
The last day of February each year is designated as Rare Disease Day, a unique opportunity to recognize people who sometimes seem to be forgotten by the mainstream medical community….