Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
Prevalent Methylation in Prokaryotic Genomes Suggests Regulatory Functions
A new publication from scientists at Lawrence Berkeley National Laboratory, the Joint Genome Institute, and other organizations reports a landmark study of genome-wide methylation in prokaryotes. The analyses of 230…
On Rare Disease Day, celebrating the contributions of genomics
Today we are celebrating Rare Disease Day with like-minded folks all over the world. The tribute kicked off in 2008 and has gathered so much momentum that people in more…
New Views of Microbial Communities Call for Updates to Infectious Disease Tenets
In a perspective recently published in Science magazine, scientists Allyson Byrd and Julie Segre from the National Human Genome Research Institute used recent advances in microbial analysis to look at…
15th Anniversary of the Human Genome Publication; A Conversation with Mike Hunkapiller
This month serves as the 15th anniversary of the first publication of the human genome by both public and private efforts. PacBio CEO Mike Hunkapiller was a central player in…
AGBT Day 4: A Better Gorilla Assembly, and Data from the Sequel System
On the final day of AGBT, attendees strapped in for the last talks of the conference before the ’80s-themed dance party to close out the meeting. Two of those talks focused on…
AGBT Day 3: Human Genomes and Their Microbial Friends
We’ve been in the genomics world long enough to remember when it was a big deal to see a great single-gene assembly or microbial genome assembly reported in an AGBT…
AGBT Days 1 & 2: Metagenomic Dark Matter and the GenomeAsia 100K
This year’s AGBT presentations took our minds off how much we missed the Marco Island beach. Wednesday’s opening plenary talks ranged from the ocean virome to Ebola and beyond. David…
AGBT Workshop: Live Stream Video
Here’s the video of our AGBT 2016 workshop. We’d like to thank our speakers for a great event. Enjoy!
Discover the Art of SMRT Sequencing:
AGBT Kicks Off This Week
We’re packing our bags for Orlando and the 17th annual Advances in Genome Biology and Technology (AGBT) conference! While we’ll miss the usual Marco Island setting, this year’s talks and…
Genome Galaxy Initiative:
Tick Hunter Cory Gall Seeks to Trace the Cause of Acute Febrile Illness
We recently introduced our Genome Galaxy Initiative in partnership with Experiment, through which we’re helping scientists fund genomic research for the benefit of science and society. One of the first…
Scientists Investigate Minor Influenza Strains in Pandemic, Revealing New Clues in Flu Transmission
On the heels of her remarkable paper tracing influenza evolution in a single host last spring, New York University’s Elodie Ghedin has come out with a new publication in Nature…
A Genome Galaxy Not So Far Away
Blog readers know that we are committed to supporting open-access research, from working with the informatics developer community to develop improved tools to releasing SMRT Sequencing data so scientists can…
From Genetic Diagnosis to a Career in Genomics Research: An Interview with Jim Lupski
For Jim Lupski, his long-standing interest in the field of genomics is both personal and professional. His personal interest dates from his teenage years, when he was diagnosed with a…
Case study: Comprehensive view of maize genome offers regulatory insight
When Doreen Ware and her team’s latest genome project is complete, the plant science community will have a critical new tool that once seemed virtually impossible: a robust reference assembly…
Scientists Develop More Accurate Variant-Calling Procedure for Important Drug Metabolism Enzyme Using SMRT Sequencing
In an article entitled “Long-read single-molecule real-time (SMRT) full gene sequencing of cytochrome P450-2D6 (CYP2D6)” in Human Mutation, authors Wangiong Qiao, Yao Yang, Stuart Scott and other colleagues at the…