Blog
February 19, 2026
Radboud UMC research highlights promise of HiFi long-read sequencing to match standards of care in rare disease genomics
When you work in rare disease, you recognize the pattern: Test. Wait. Repeat. For families, that loop is a stretch of time that includes birthdays, school years, and treatment…
February 12, 2026
Rare Disease Month: Taking a People-First approach in the global fight against rare disease
Rare diseases are often described in numbers. Prevalence rates. Case counts. Years to diagnosis. But for families living with rare disease, those numbers are only part of the story….
February 5, 2026
How SPRQ-Nx enables affordable long-read whole genome sequencing without added complexity
Long-read whole genome sequencing is starting to show up in places it rarely could before. With the introduction of SPRQ-Nx, HiFi sequencing has now become the most affordable long-read…
January 29, 2026
Beyond the Bench: Advancing cancer transcriptomics with HiFi long-read RNA sequencing
With the PacBio Beyond the Bench video series now live, we’re feeling the enthusiasm surrounding a personal look at scientists’ lives and the rituals that anchor their work. This…
January 22, 2026
Publication spotlight: HiFi sequencing enables haplotype-specific chromatin mapping from single cells using DAF-seq
Oftentimes in biology, the biggest advances come from new ways of measuring complex systems, rather than a single discovery in itself. This publication spotlight highlights a recent Nature Biotechnology…
January 15, 2026
2025 Epigenetics SMRT Grant Awardees
Epigenetics offers critical insight into how the genome is regulated beyond DNA sequence alone, shaping cellular identity, function, and disease. Along with our co-sponsor EpiCypher, we are excited to…
January 9, 2026
A year in review: HiFi in the Headline
It’s 2026 and there’s no better time than now to look back at 2025 and celebrate its meaningful impact in genomics. In 2025, PacBio focused on driving technical advances,…
December 23, 2025
Meet the winners of the 2025 long-read low-pass SMRT Grant for plant and animal sciences
As we head into the holiday season, we are more excited than ever to share some good news by announcing the winners of the 2025 Long-read Low-pass SMRT Grant…
December 18, 2025
Beyond the Bench:
A series celebrating the people behind scientific progress
When the lights turn on in a genomics lab, the day is already in motion. Boxes of samples wait to be logged, barcodes are scanned, concentrations get double-checked and…
December 11, 2025
Sequencing 101: A long-read sequencing starter guide for every career stage
The challenges of bringing on new technology feel surprisingly similar regardless of career stage or field. Grad students, bioinformaticians, PIs, and professionals running core facilities all want to make…
December 4, 2025
Powered by PacBio:
Selected publications from November 2025
November’s standout publications show how PacBio technology is impacting advances in human genomics research. This month’s selection includes studies on accurate variant detection in paralogous genes, a new visualization…
November 26, 2025
How long-read sequencing informs the future of food from genome to table
Thanksgiving is almost here, and we’re filled with gratitude for the food on our tables and the science that helps make this possible. From the corn in a casserole…
November 24, 2025
Publication spotlight:
First major study from the HiFi Solves EMEA consortium showcases the potential clinical power of a HiFi genome
We just got back from the Molecular Pathology (AMP) conference in Boston, where the conversation around clinical research and translational genomics was in full motion. The field is moving…
November 13, 2025
How pairing EpiCypher’s Fiber-seq with HiFi sequencing delivers an all-in-one multiomic view
As genetics research evolves, scientists are recognizing that it’s not just the DNA sequence that matters, it’s how that DNA is packaged. The study of epigenetics, how chromatin structure…
November 7, 2025
Powered by PacBio:
Selected publications from October 2025
This month’s roundup showcases the diverse ways researchers are using PacBio technology to uncover new insights across population genomics, cancer research, neurodegenerative disease, and precision medicine. In the October…