October 20, 2025 | Educational video

PureTarget: PCR-Free Enrichment with Methylation for Challenging Genes

PacBio Field Application Scientist Samantha Kalla details PureTarget, a powerful PCR-free method for targeted sequencing that preserves native methylation data. Learn how this CRISPR-Cas9-based approach enables the comprehensive analysis of challenging genomic regions, including GC-rich areas and repeat expansions, by enriching for targets directly from high-molecular-weight DNA.

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