April 21, 2020  |  

The Genome Sequence of the Anthelmintic-Susceptible New Zealand Haemonchus contortus.

Authors: Palevich, Nikola and Maclean, Paul H and Baten, Abdul and Scott, Richard W and Leathwick, David M

Internal parasitic nematodes are a global animal health issue causing drastic losses in livestock. Here, we report a H. contortus representative draft genome to serve as a genetic resource to the scientific community and support future experimental research of molecular mechanisms in related parasites. A de novo hybrid assembly was generated from PCR-free whole genome sequence data, resulting in a chromosome-level assembly that is 465 Mb in size encoding 22,341 genes. The genome sequence presented here is consistent with the genome architecture of the existing Haemonchus species and is a valuable resource for future studies regarding population genetic structures of parasitic nematodes. Additionally, comparative pan-genomics with other species of economically important parasitic nematodes have revealed highly open genomes and strong collinearities within the phylum Nematoda. © The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Journal: Genome biology and evolution
DOI: 10.1093/gbe/evz141
Year: 2019

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