April 21, 2020  |  

Salmonella harbouring the mcr-1 gene isolated from food in China between 2012 and 2016.

Authors: Hu, Yujie and Fanning, Séamus and Gan, Xin and Liu, Chang and Nguyen, Scott and Wang, Meimei and Wang, Wei and Jiang, Tao and Xu, Jin and Li, Fengqin

In November 2015, plasmid-mediated transferable colistin resistance encoded by the mcr-1 gene in Escherichia coli and Klebsiella pneumonia isolates was reported in China with a high rate of in vitro horizontal transfer (10-1–10-3 cells per recipient cell by conjugation).1 At that time, the mcr-1 gene had already been identified in >30 countries across five continents, with novel mcr-2, mcr-3, mcr-4 and mcr-5 genes being reported subsequently.2–5 Recently, a surveillance study was performed on mainland China to investigate the prevalence of the mcr-1 gene in foodborne Salmonella isolates isolated from various food matrices and others collected...

Journal: The Journal of antimicrobial chemotherapy
DOI: 10.1093/jac/dky496
Year: 2019

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