July 7, 2019  |  

IWTomics: testing high-resolution sequence-based ‘Omics’ data at multiple locations and scales.

Authors: Cremona, Marzia A and Pini, Alessia and Cumbo, Fabio and Makova, Kateryna D and Chiaromonte, Francesca and Vantini, Simone

With increased generation of high-resolution sequence-based 'Omics' data, detecting statistically significant effects at different genomic locations and scales has become key to addressing several scientific questions. IWTomics is an R/Bioconductor package (integrated in Galaxy) that, exploiting sophisticated Functional Data Analysis techniques (i.e. statistical techniques that deal with the analysis of curves), allows users to pre-process, visualize and test these data at multiple locations and scales. The package provides a friendly, flexible and complete workflow that can be employed in many genomic and epigenomic applications.IWTomics is freely available at the Bioconductor website ( and on the main Galaxy instance ( data are available at Bioinformatics online.

Journal: Bioinformatics
DOI: 10.1093/bioinformatics/bty090
Year: 2018

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