High-quality draft genome sequence of the actinobacterium Nocardia terpenica IFM 0406, producer of the immunosuppressant brasilicardins, using Illumina and PacBio technologies.

Authors: Buchmann, Anina and Eitel, Michael and Koch, Pierre and Schwarz, Paul N and Stegmann, Evi and Wohlleben, Wolfgang and Wolanski, Marcin and Krawiec, Michal and Zakrzewska-Czerwinska, Jolanta and Méndez, Carmen and Botas, Alma and Núñez, Luz Elena and Morís, Francisco and Cortés, Jesus and Gross, Harald

The bacterium Nocardia terpenica IFM 0406 is known as the producer of the immunosuppressant brasilicardin A. Here, we report the completely sequenced genome of strain IFM 0406, which facilitates the heterologous expression of the brasilicardin biosynthetic gene cluster but also unveils the intriguing biosynthetic capacity of the strain to produce secondary metabolites. Copyright © 2016 Buchmann et al.

Journal: Genome announcements
DOI: 10.1128/genomeA.01391-16
Year: 2016

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