Genomic analysis of three Clostridioides difficile isolates from urban water sources.

Authors: Numberger, Daniela and Riedel, Thomas and McEwen, Gayle and Nübel, Ulrich and Frentrup, Martinique and Schober, Isabel and Bunk, Boyke and Spröer, Cathrin and Overmann, Jörg and Grossart, Hans-Peter and Greenwood, Alex D

We investigated inflow of a wastewater treatment plant and sediment of an urban lake for the presence of Clostridioides difficile by cultivation and PCR. Among seven colonies we sequenced the complete genomes of three: two non-toxigenic isolates from wastewater and one toxigenic isolate from the urban lake. For all obtained isolates, a close genomic relationship with human-derived isolates was observed.Copyright © 2019 Elsevier Ltd. All rights reserved.

Journal: Anaerobe
DOI: 10.1016/j.anaerobe.2019.01.002
Year: 2019

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