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July 7, 2019  |  

Dissemination of the mcr-1 colistin resistance gene.

Authors: Zhi, Chanping and Lv, Luchao and Yu, Lin-Feng and Doi, Yohei and Liu, Jian-Hua

Since our first report on plasmid- mediated colistin resistance gene mcr-1,1 strains previously collected in seven countries (Denmark, the Netherlands, Laos, Nigeria, Thailand, France, and the UK) have been found to carry mcr-1.2–6 Furthermore, the sequences in GenBank show that mcr-1 might also be circulating in Portugal and Malaysia. The earliest mcr-1- positive strain was collected from cattle in France in 2008 (GenBank accession number LMBK01000308). These findings confirm our initial concern that mcr-1 could have already disseminated worldwide.

Journal: The Lancet. Infectious diseases
DOI: 10.1016/S1473-3099(16)00063-3
Year: 2016

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