September 22, 2019  |  

Catching up with Lyme disease antigenic variation computationally.

Authors: Norris, Steven J

The spirochetes that cause Lyme disease have an elaborate antigenic variation system that produces millions of variants, thus evading the immune response. Verhey et al. have applied next-generation sequencing and computational analysis to gain new insights into how these bacteria keep 'one step ahead' of elimination by the host. Copyright © 2018 Elsevier Ltd. All rights reserved.

Journal: Trends in microbiology
DOI: 10.1016/j.tim.2018.05.017
Year: 2018

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