Pacific Biosciences of California, Inc. Announces Third Quarter 2012 Financial Results

MENLO PARK, Calif., Oct. 25, 2012 (GLOBE NEWSWIRE) — Pacific Biosciences of California, Inc. (Nasdaq:PACB) today announced financial results for the third quarter ended September 30, 2012.

During the third quarter of 2012, the Company recognized revenue from SMRT^® Cell and reagent consumables, instrument service contracts and grants. Revenue for the third quarter of 2012 totaled $2.8 million compared to revenue of $7.3 million for the second quarter of 2012. Net loss for the quarter was $22.7 million compared to the $22.5 million net loss during the second quarter of 2012.

Gross profit for the third quarter of 2012 totaled $0.2 million, resulting in a gross margin of 7%, compared to a $0.3 million gross profit for the second quarter of 2012 and a gross margin of 4%. Gross profit for the third quarter of 2011 was $3.3 million representing a gross margin of 32%. The gross margin for the third quarter 2011 reflects the positive margin impact of instrument components expensed prior to the Company’s commercial launch during the second quarter of 2011.

Operating expenses totaled $22.8 million for both the second and third quarters of 2012. Operating expenses in the third quarter of 2012 include $2.3 million of non-cash stock-based compensation with $1.2 million and $1.1 million recorded in research and development, and selling, general and administrative expenses, respectively. Operating expenses in the third quarter of 2011 were $32.8 million.

Cash and investments at September 30, 2012 totaled $119.4 million compared to $137.1 million at June 30, 2012.

The Company’s system revenue backlog of 5 units as of September 30, 2012 represents an order for one PacBio RS instrument received during the second quarter of 2012 and four PacBio RS instruments orders received during the third quarter of 2012.

Quarterly Conference Call Information

Management will host a quarterly conference call to discuss its third quarter 2012 results today at 4:30pm Eastern / 1:30pm Pacific. Investors may listen to the call by dialing 888.366.7247, or if outside the U.S., by dialing +1.707.287.9330. The call will be webcast live and will be available for replay at Pacific Biosciences’ website at http://investor.pacificbiosciences.com/ .

About Pacific Biosciences

Pacific Biosciences of California, Inc. (Nasdaq:PACB) offers the PacBio^® RS High Resolution Genetic Analyzer to help scientists solve genetically complex problems. Based on its novel Single Molecule, Real-Time (SMRT^®) technology, the company’s products enable: targeted sequencing to more comprehensively characterize genetic variations; de novo genome assembly to more fully identify, annotate and decipher genomic structures; and DNA base modification identification to help characterize epigenetic regulation and DNA damage. By providing access to genetic information that was previously inaccessible, Pacific Biosciences enables scientists to increase their understanding of biological systems.

Forward-Looking Statements

This press release contains forward-looking statements relating to the Company’s operations and operating results, including statements relating to the Company’s revenue. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties and other factors that are, in some cases, beyond the Company’s control and that could materially affect actual results. Factors that could materially affect actual results can be found in Pacific Biosciences of California’s filings with the Securities and Exchange Commission, including the most recently filed Quarterly Report on Form 10-Q, including those listed under the caption “Risk Factors.” Pacific Biosciences of California expressly disclaims any intent or
obligation to update these forward-looking statements, except as required by law.

CONTACT: Trevin Rard

         650.521.8450

         ir@pacificbiosciences.com

Source: Pacific Biosciences of California, Inc.

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