Blog
April 3, 2025
Customer success story: The University of Bern takes long-read sequencing to the next level with SPRQ chemistry
The new SPRQ chemistry for the Revio system is making high-quality long-read sequencing more efficient than ever—delivering more data from less input without compromising accuracy or cost efficiency. But…
March 27, 2025
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Selected publications from March 2025
This month’s publications show how PacBio HiFi sequencing is being used to address complex problems in clinical genetics, brain research, and crop development. The March 2025 edition of our…
March 18, 2025
Inspiring the next generation of scientists: How multidisciplinary science powers PacBio technology
PacBio is hitting the pavement this weekend for the Seq It Forward 5K + Fun Run, backing San Diego LabRats and hands-on STEM education. Science starts young, and this event…
March 13, 2025
2024 SMRT Conserve grant winners
At PacBio, we see genomics as a powerful way to help protect Earth’s biodiversity. Around the world, researchers are working to sequence tens of thousands of species, gaining insights…
March 6, 2025
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Selected publications from February 2025
HiFi sequencing continues to drive discoveries across research areas, from chromatin architecture to immune system diversity and gene therapy safety. In the February 2025 edition of Powered by PacBio,…
February 27, 2025
Rare Disease Month: Putting People First
As February comes to a close, we approach Rare Disease Day on February 28 and reflect on the purpose behind our work in rare disease research. At PacBio, our…
February 20, 2025
How HiFi sequencing is making a difference for rare disease research at Children’s Mercy
A rare disease can be an immense burden on patients and families, especially when it comes to childhood conditions. The path from symptoms to diagnosis to treatment is often…
February 13, 2025
How HiFi sequencing lays the groundwork for accelerating rare disease diagnostics in the clinic
In February we are observing Rare Disease Month, a time to shine a light on the experiences of rare disease patients and their families. At PacBio, we are committed…
February 6, 2025
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Selected publications from January 2025
The start of 2025 is proving to be an influential moment for long-read sequencing, with a surge of research showcasing the power of PacBio HiFi sequencing. This month, we’re…
January 30, 2025
Sequencing 101: Epigenetics
Epigenetics is all about understanding how gene activity can change without altering the DNA sequence itself. Think of it as a “volume control” for your genes, turning them up…
January 23, 2025
Publication spotlight: Advancing plant breeding with long-read low-pass sequencing
We are energized from celebrating a Bright New Day at PAG last week! We had a fantastic time connecting with the plant and animal genomics community through collaborative discussions…
January 13, 2025
New Ampli-Fi ultra-low-input protocol will support HiFi sequencing from as little as 1 ng of DNA
Highly accurate long-read sequencing technologies have made it possible to generate genome assemblies at scale. In fact, HiFi sequencing is now the technology of choice for assembling reference-quality genomes…
January 9, 2025
PacBio 2024 Wrapped: A year of breakthroughs by the numbers
Onso short-read sequencing systems are no longer available through PacBio As we welcome a new year, we’re energized by what’s ahead—because of what we’ve accomplished together. 2024 was a…
January 3, 2025
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Selected publications from December 2024
As we close out 2024, the power of PacBio technology has never been more evident. December brought an inspiring array of research that highlights how HiFi sequencing is driving…
December 24, 2024
A father’s journey: finding hope through genomics
In Austin, Texas, Casey McPherson balances many roles—musician, entrepreneur, and most importantly, dad to his two daughters, Weston and Rose. But beneath the day-to-day rhythms of family life lies…