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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

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Publication spotlight: Advancing plant breeding with long-read low-pass sequencing

We are energized from celebrating a Bright New Day at PAG last week! We had a fantastic time connecting with the plant and animal genomics community through collaborative discussions…

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New Ampli-Fi ultra-low-input protocol will support HiFi sequencing from as little as 1 ng of DNA

Highly accurate long-read sequencing technologies have made it possible to generate genome assemblies at scale. In fact, HiFi sequencing is now the technology of choice for assembling reference-quality genomes…

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PacBio 2024 Wrapped: A year of breakthroughs by the numbers

Onso short-read sequencing systems are no longer available through PacBio As we welcome a new year, we’re energized by what’s ahead—because of what we’ve accomplished together. 2024 was a…

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Selected publications from December 2024

As we close out 2024, the power of PacBio technology has never been more evident. December brought an inspiring array of research that highlights how HiFi sequencing is driving…

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A father’s journey: finding hope through genomics

In Austin, Texas, Casey McPherson balances many roles—musician, entrepreneur, and most importantly, dad to his two daughters, Weston and Rose. But beneath the day-to-day rhythms of family life lies…

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Garvan Institute researchers demonstrate that saliva samples are viable for long-read sequencing

Population studies, direct-to-consumer genetic tests, biobanks, and other large-scale genomic research projects rely on DNA gathered from saliva samples, which are often self-collected and submitted by the general public….

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Selected publications from November 2024

On the heels of ASHG, we are proud to see researchers leading the way with HiFi sequencing as the tool of choice to make groundbreaking discoveries. We are encouraged…

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Lighting a SPRQ: How new Revio chemistry fuels innovative research

The genomics world is buzzing. A few weeks ago, PacBio introduced SPRQ chemistry for its Revio system, a leap forward for HiFi sequencing technology that’s igniting excitement among researchers…

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Gaining deeper insight with targeted sequencing

Onso short-read sequencing systems are no longer available through PacBio Big things are happening at PacBio! The latest launches of the Vega system and SPRQ chemistry are creating quite…

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Introducing the Vega system – HiFi sequencing within reach

The first benchtop HiFi long-read sequencing platform is now here with Vega, named after one of the brightest stars in the sky. This exciting platform builds out the…

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Selected publications from October 2024

PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across…

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What are genomic variants and why do they matter?

The genetic blueprint of every living organism, from humans to microbes, is written in DNA. This blueprint is shaped by a remarkable phenomenon: genetic variation. These variations, or differences…

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The truth about sequencing accuracy and how PacBio leads the way

Onso short-read sequencing systems are no longer available through PacBio HiFi sequencing enables next-level accuracy in DNA sequencing. But did you know that level of accuracy extends throughout the…

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Child Health Day 2024 – the power of HiFi sequencing in rare disease research

Children’s health is central to our future. That’s why we set aside the first Monday of October as Child Health Day to raise awareness about the importance of children’s…

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Selected publications from September 2024

PacBio HiFi sequencing technology continues to offer industry-leading results that enable researchers to explore uncharted territory across a variety of biological fields. The exceptional accuracy of HiFi sequencing drives…

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