Blog
October 17, 2013
Stanford Team Finds Novel Transcripts Using Long-Read Isoform Sequencing
An advance online publication in Nature Biotechnology from Michael Snyder’s lab at Stanford University demonstrates the utility of long-read sequencing for assessing transcribed regions across the human genome. Long PacBio…
October 9, 2013
Resolving Complex Regions in the Human Genome: SMRT Sequencing Fills Major Mucin Gap
Scientists from University of North Carolina at Chapel Hill, Duke University, and other institutions have teamed up to sequence an important region of the human genome that has until now…
October 7, 2013
Characterizing Structural Variation in the Human Genome: ASHG 2013 Workshop and Presentations
We are excited to participate in the annual American Society of Human Genetics meeting again this year on October 22-26 in Boston, MA. With so many new PacBio® technology advances…
October 3, 2013
New Chemistry for PacBio RS II Provides Average 8.5 kb Read Lengths for Complex Genome Studies
Our R&D team has been focusing on chemistry improvements for the PacBio® RS II sequencer and today we are pleased to announce our newest reagent combination, the P5 DNA polymerase…
September 16, 2013
Genome Biology Paper Highlights Affordability and Scale of PacBio-Based Finished Microbial Genomes
A new paper released in Genome Biology on September 13 from lead author Sergey Koren at the National Biodefense Analysis and Countermeasures Center offers a thorough overview of SMRT® Sequencing…
September 5, 2013
Next Week’s ICG Meeting to Include Several SMRT Sequencing Talks
The International Conference on Genomics in the Americas (ICG), organized by BGI and UC Davis, is taking place on Sept 12-13 in Sacramento, CA. One of the keynote presentations in…
September 3, 2013
New Data Release: Arabidopsis Assembly Offers Glimpse of
De Novo SMRT Sequencing for Larger Genomes
Update 1/13/14: A new data release of Arabidopsis using P5-C3 chemistry is available Advances in our chemistries, throughput, and read length are pushing the envelope in the way we tackle…
August 27, 2013
Oklahoma Scientists Use SMRT Sequencing to Rescue Fungal Genome Assembly
Orpinomyces is found in cattle rumen. Scientists from Oklahoma State University and the University of Oklahoma teamed up with a sequencing service provider to study the genome of an anaerobic…
August 22, 2013
The Value of Finished Bacterial Genomes: A Microbiology Primer
Microbiologists have been at the forefront of genomics since Haemophilus influenzae became the first organism to have its full genome sequenced in 1995 using Sanger sequencing. Even with modern technology,…
August 21, 2013
New DNA Polymerase P4 Delivers Higher-Quality Assemblies Using Fewer SMRT Cells
Pacific Biosciences is pleased to announce the introduction of DNA/Polymerase Binding Kit P4. This P4 enzyme has average read lengths of >4,300 bp when paired with the C2 sequencing chemistry…
August 19, 2013
Scientists Assess Error Modes in Sequencing Platforms and Find SMRT Sequencing ‘Least Biased’
A paper from scientists at the Broad Institute reports a rigorous study of bias across all major sequencing platforms. In “Characterizing and measuring bias in sequence data,” published in Genome…
August 1, 2013
#SMRTSeq Tweet Chat: Users Weigh in on Current Applications and Future Outlook for PacBio Sequencing
Today offered something new for the PacBio® team: our SMRT® technology was the subject of a tweet chat hosted by Genome Biology. For one hour, editors at the journal along…
July 30, 2013
Single-Molecule Sequencing Technology Q&A with Nobel Laureate Rich Roberts
BioMed Central has published an interesting Q&A session on its Biome blog with Nobel Laureate Richard Roberts about why he believes in SMRT Sequencing and thinks non-users should take another…
July 29, 2013
As Cores Upgrade to PacBio RS II, Users Report Data and Progress
As PacBio customers are upgrading to the new PacBio® RS II System, some of our core lab users have already begun blogging about the improved results. At the University of…
July 22, 2013
New Genomes for 100K Pathogen Project Sequenced and Finished with PacBio Technology
The 100K Foodborne Pathogen Genome Project announced the contribution of 20 newly finished genomes of microbes responsible for foodborne disease, and we’re pleased to report that they were sequenced and…