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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

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PNAS: Copy Number Analysis in Maize Sheds Light on Tolerance for Acidic Soil

A new study of maize sheds light on the importance of copy-number variation in genes related to stress tolerance with implications to boost crop yield in suboptimal soil environments. A…

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Current Opinion in Microbiology: Bacterial Methylomes in Review – ‘An Exciting Era’

A new review paper from Brigid Davis, Michael Chao, and Matthew Waldor at Harvard Medical School considers a number of recent studies and findings that have used single molecule, real-time…

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Guest Blog: Michael Schatz shares his perspective on the new PacBio RS II

Michael Schatz, Ph.D. Assistant Professor of Quantitative Biology at Cold Spring Harbor Laboratory, shares some thoughts about his experience with the PacBio RS and his hopes for future work with…

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Rapid Genome Assembly: Salmonella Outbreak Strain Sequenced and Closed in Less Than One Week

A newly reported Salmonella genome showcases the utility of single molecule, real-time (SMRT®) sequencing for characterizing a foodborne outbreak pathogen. The outbreak strain, Salmonella enterica subsp. enterica serovar Javiana (S….

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It’s a Very Microbial Season

This springtime, we’ve got microbes on the brain! The annual meeting of the American Society for Microbiology is just over a month away, so we’ve been thinking a lot about…

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Want to Try Out the PacBio RS? Our Sequencing Providers Can Help

It has been really gratifying to see that interest in Single Molecule, Real-Time (SMRT®) Sequencing has been steadily increasing — there seems to be lots of pent-up demand to run…

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Sequencing Innovations Offer a More Complete Picture for Microbes

We’re pleased to share with you a recent article from Microbe magazine, a publication of the American Society for Microbiology, from Eric Schadt, founding director of the Icahn Institute for…

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Going to ASM? Register Now for the Microbial Epigenetics Workshop on May 18

If you’ll be heading to Denver for the American Society for Microbiology annual meeting on May 18-21, don’t miss the pre-conference workshop on whole-genome microbial epigenetics. New studies are continually…

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From In Sequence: Spotlight on PacBio Customers’ Data at AGBT 2013

A recent article from In Sequence highlights several of our customers and the great projects they’ve been working on with single molecule, real-time (SMRT®) sequencing. If you’re not a subscriber…

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AGBT Day 4 Highlights: SMRT Sequencing for De Novo Genome Assemblies

Even as attendees’ energy was waning from three marathon days at AGBT, spirits were still high as we gathered for the final day’s Genomic Technologies session on Saturday morning. This…

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AGBT Day 3 Highlights: Long-Read Sequence Data Makes a Difference for Human, Crop Studies

The third day of sessions has wrapped up at AGBT, and we’ve got one day left to go. It’s the last leg of the marathon! We’ve been having a great…

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AGBT Day 2 Highlight: Bovine Immune Response Characterized with PacBio Sequencing

We survived the second day of AGBT, and the conference is officially in full swing. After an intense day of sessions focused on clinical genomics, the evening took us back…

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AGBT Day 1 Highlights: Focus on Epigenetics

Years ago, “epigenetics” was largely synonymous with methylation — in particular, 5-methylcytosine, which could be analyzed through bisulfite sequencing. Today, technologies have advanced and so has our understanding of the…

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AGBT 2013: Meeting Preview & PacBio Activities

This week we are fortunate to be attending the annual Advances in Genome Biology & Technology (AGBT) meeting in Marco Island, FL. The conference is always jam-packed with top tier…

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Mendelspod Interview with Mike Hunkapiller, CEO of Pacific Biosciences

Mike Hunkapiller was interviewed for a podcast recently on Mendelspod. In it, Mike and Mendelspod host Theral Timpson chat about the current sequencing technology landscape, clinical applications of sequencing, and…

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