Blog
January 21, 2016
From Genetic Diagnosis to a Career in Genomics Research: An Interview with Jim Lupski
For Jim Lupski, his long-standing interest in the field of genomics is both personal and professional. His personal interest dates from his teenage years, when he was diagnosed with a…
January 19, 2016
Case study: Comprehensive view of maize genome offers regulatory insight
When Doreen Ware and her team’s latest genome project is complete, the plant science community will have a critical new tool that once seemed virtually impossible: a robust reference assembly…
January 6, 2016
Scientists Develop More Accurate Variant-Calling Procedure for Important Drug Metabolism Enzyme Using SMRT Sequencing
In an article entitled “Long-read single-molecule real-time (SMRT) full gene sequencing of cytochrome P450-2D6 (CYP2D6)” in Human Mutation, authors Wangiong Qiao, Yao Yang, Stuart Scott and other colleagues at the…
January 5, 2016
Exploring Large Genomes at the Largest Ag Genomics Meeting in the World: PAG 2016
We’re looking forward to the International Plant and Animal Genome conference, taking place January 9-13 in San Diego. PAG features leading plant and animal scientists from around the world, and…
December 2, 2015
PMWC 2016: Advancing Genomics for Improved Patient Care
We’re already looking forward to next month’s Personalized Medicine World Conference. Long before “precision medicine” was an industry catchphrase, PMWC was bringing together stakeholders from genomics companies and academic research,…
November 16, 2015
Scientists Use the Iso-Seq Method to Study Genes Linked to Prostate Cancer
A team of scientists from Australia, Canada, and the US published fascinating new work that may help explain gene expression patterns seen in prostate cancer. In the course of the…
November 11, 2015
Scientists Publish High-Quality, Near-Complete Genome of Resurrection Grass Oropetium
We’re excited about a new Nature paper from the winners of our 2014 “Most Interesting Genome in the World” SMRT Grant program. “Single-molecule sequencing of the desiccation tolerant grass Oropetium…
November 9, 2015
Steven Marsh from Anthony Nolan Discusses the Past and Future of Donor Matching
Mendelspod host Theral Timpson recently interviewed Professor Steven Marsh, Director of Bioinformatics at the Anthony Nolan Research Institute, a UK-based organization dedicated to improving the outcomes of bone marrow transplantation…
November 2, 2015
Welcome to Silicon Valley, Festival of Genomics!
This week the Festival of Genomics comes to the West Coast, and we’re excited to be a founding sponsor of the Front Line Genomics organization. Not only is it our…
October 22, 2015
Scientists Sequence Klebsiella Strain Resistant to All Known Antibiotics
A new publication reports the discovery and analysis of a nightmare bacterium that’s genetically resistant to all commercially available classes of antibiotics. The paper, “Stepwise evolution of pandrug-resistance in Klebsiella pneumonia,”…
October 21, 2015
Guest Blog: Rich Roberts Urges Scientists to ‘Think Methylation’ in Microbial Sequencing
Richard Roberts, Nobel Laureate and Chief Scientific Officer of New England Biolabs, offers his thoughts on the utility of methylation data for understanding prokaryotes. In his words: “Please run SMRT…
October 20, 2015
Scientists Reveal Recent Autosome-to-Y Duplication Event in Drosophila
Following on the heels of characterizing 18 Mst77Y genes that were tandemly duplicated within a 96 kb region (Krsticevic FJ, et al., 2015), scientists from institutes in Brazil, Austria, and the…
October 15, 2015
ASHG 2015: Highlights from the Platinum Genome Session and More
During the final days of the ASHG meeting last week in Baltimore, a number of scientists offered great presentations based on data generated with SMRT Sequencing, including an entire session…
October 13, 2015
ASHG 2015: Highlights from Icahn Institute, UW, Stanford & CSHL Presentations
During the Wednesday afternoon sessions of last week’s ASHG conference, several speakers provided helpful insights about their use of SMRT Sequencing for a range of applications. Highlights included the following:…
October 9, 2015
ASHG Workshop Recap & Recording: Addressing Hidden Heritability with SMRT Sequencing
The PacBio workshop at ASHG 2015 featured talks from two leaders in human genomics, Rick Wilson of Washington University and Richard Gibbs from Baylor University. Mike Hunkapiller, CEO of Pacific…