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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

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At AACR, Revealing Structural Variants and a New SMRT Grant Program

We’re excited to be heading to Washington, DC, for the annual meeting of the American Association for Cancer Research. The PacBio team always enjoys hearing about the latest in cancer…

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IGV 3 Improves Support for PacBio Long Reads

The recent beta release of version 3 of the popular genome browser IGV greatly improves support for PacBio data [1]. The long reads (up to 50 kb) and random error…

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Scientists Confirm Transplant-Associated Infection with SMRT Sequencing

A new PLoS One publication cites the use of SMRT Sequencing to clarify the transmission path of infection in a transplant recipient. This work is an excellent example of the…

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Metal-Devouring Plant Genomes Get SMRT Treatment with Sequel System: 2016 SMRT Grant Program Winner Results

Blog readers may recall that last year’s SMRT Grant winner was Renying Zhuo from the Chinese Academy of Forestry. We’re pleased to report that the project is now complete! Zhuo…

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New Goat Genome Assembly Breaks Continuity Record, Expands Breeding Tools

Efforts to produce a reference-grade goat genome assembly for improved breeding programs have paid off. A new Nature Genetics publication reports a high-quality, highly contiguous assembly that can be used…

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Vote for the World’s Most Interesting Genome! Snakes, Slugs, Pigeons, Beetles & Dingoes Compete for SMRT Sequencing Treatment

Our team of scientist reviewers has considered hundreds of submissions for the latest SMRT Grant award and narrowed the selection to five finalists. Now it’s your turn! We welcome the…

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High-Quality, Chromosome-Scale Quinoa Genome Valuable for Breeding Better Crops

A new genome assembly has remarkable promise to boost the global food supply. Scientists from King Abdullah University of Science and Technology and other institutions sequenced quinoa, a nutritious grain…

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‘Mobilome’ Study of Antibiotic Resistance Implicates Transposon Activity

A recent effort to understand the genetic mechanisms behind swappable elements of drug-resistance among bacteria built on previous studies of Enterobacteriaceae isolates collected at the National Institutes of Health Clinical Center….

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Scientists explore extremophile genome with SMRT sequencing

A recent Nature publication from a large team of scientists in Europe, Canada, and the US reports the use of SMRT Sequencing to elucidate the genome of Fragilariopsis cylindrus, a…

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AGBT 2017, Day 2: Diploid Genomes, Deep Learning, and the PacBio Workshop

The second day of AGBT featured a number of great talks and posters, and also our user workshop called “Covering All the Bases with SMRT Sequencing.” We’d like to thank…

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AGBT 2017, Day 1: Infectious Disease and Improved Genome Assemblies

We’re thrilled to be at the AGBT conference this week, taking place this year in Hollywood, Fla. On the first full day of the meeting, everyone’s mandatory wristbands look shiny…

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Staying on Top of Long-Read Sequencing at AGBT 2017

We’re heading cross-country to the Advances in Genome Biology and Technology (AGBT) Meeting starting Monday in sunny Hollywood, Florida. There will be several great opportunities to learn about how scientists…

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PAG Workshop: Wide Breadth of Research Benefiting from SMRT Sequencing

If you didn’t get to the Plant and Animal Genome meeting this year, you missed a great workshop featuring SMRT Sequencing users and the fascinating projects they’re working on across…

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Toward a Gold Standard for Human Structural Variation

Scientists from the University of Washington and McDonnell Genome Institute recently reported in Genome Research the results of an in-depth assessment of structural variation in the human genome using SMRT…

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Scientists Produce Reference Genome for Plasmodium, Update Phylogeny

A new Nature paper from scientists at the Wellcome Trust Sanger Institute and other institutions delves into two Plasmodium genomes and reveals novel information about how these parasites have evolved. SMRT…

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