Blog
October 30, 2025
Publication spotlight:
Capturing the full picture of genome editing with custom PureTarget panels
In genome editing, precision is the goal, but biology has a way of introducing variation of its own. Genetic mosaicism occurs when different genetic variants coexist within the same…
October 22, 2025
Customer success story:
How two University of Michigan cores use HiFi sequencing to cut costs, save time, and improve accuracy in transgenic models
At the University of Michigan, two cores on opposite sides of campus are working together to change what’s possible in genomics. Judith Meyers helps run the Advanced Genomics Core…
October 16, 2025
Landmark All of Us study demonstrates HiFi sequencing as the key to uncovering disease variants
This week PacBio is bringing our energy and innovation in human genomics to ASHG in Boston, and there’s no better time to learn about what we’ve been up to….
October 9, 2025
How HiFi sequencing achieves scalable microbial genomics without compromise
Microbes touch every part of our lives. They’re what make up the beneficial communities living in our guts and the pathogens that drive major public health crises. If you’re…
October 2, 2025
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Selected publications from September 2025
This month’s publications show just how versatile HiFi sequencing has become. In September, studies ranged from building the most comprehensive map yet of human genomic imprinting, to evaluating clinical…
September 25, 2025
How PureTarget is modernizing research into carrier screening
As many as 7 in 10 people carry at least one pathogenic genetic variant, even if they have no family history of disease1. That means most couples could unknowingly…
September 18, 2025
The growing importance of carrier screening in genomics
Carrier screening is one of the most influential ways genetics is shaping the future of human health. By revealing inherited risks before they ever appear, carrier screening has changed…
September 11, 2025
2025 Microbiome SMRT Grant Awardees
We are thrilled to announce the winners of the 2025 Microbiome SMRT Grant for HiFi shotgun metagenomics. This year’s program received hundreds of amazing proposals from researchers around the…
September 4, 2025
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Selected publications from August 2025
This month’s publication highlights show how HiFi sequencing is helping researchers tackle challenges across clinical genomics research. See how HiFi is helping researchers sequence ultra-low input cancer samples, profile…
August 28, 2025
Looking to make sense of your research? There’s HiFi for that
The coffee’s cold, your pipette tips are backordered, and someone just booked your favorite lab bench. Science can be full of small annoyances. We can’t solve them all, but…
August 20, 2025
Fast-track biopharma breakthroughs with HiFi long-read sequencing
In biopharmaceutical research and development, the path from discovery to approved therapy can be long and complex, requiring innovation at every step. Success depends on understanding biology at its…
August 14, 2025
Sequencing 101: How multiplexing with long-read sequencing makes genomic research faster, cheaper, and smarter
Sequencing is the backbone of modern genomics. It has evolved over time, and as platforms grow to be faster and more accurate, researchers are finding new ways to maximize…
August 8, 2025
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Selected publications from July 2025
In July 2025’s publication roundup we’re proud to show how HiFi sequencing is playing a major role in advancing our understanding of the human brain, and autism in particular….
July 31, 2025
Customer success story:
How Dr. Ibrahim Bitar is doubling his research impact while leading the future of European genomics from the Czech Republic
When it comes to microbial genomics, Dr. Ibrahim Bitar doesn’t back down from a challenge. As an Assistant Professor of Microbiology at Charles University in Prague, and CEO of…
July 24, 2025
Publication spotlight: How Kinnex long-read RNA sequencing wins out over Illumina for transcript-level quantification
Kinnex has been making a splash since the day it launched – showing up in talks, turning heads in RNA labs, and putting its use cases solidly in the…