September 22, 2019  |  

Tn6450, a novel multidrug resistance transposon characterized in a Proteus mirabilis isolate from chicken in China.

Authors: Chen, Yan-Peng and Lei, Chang-Wei and Kong, Ling-Han and Zeng, Jin-Xin and Zhang, Xiu-Zhong and Liu, Bi-Hui and Li, Yi and Xiang, Rong and Wang, Yong-Xiang and Chen, Dan-Yu and Zhang, An-Yun and Wang, Hong-Ning

A novel 65.8-kb multidrug resistance transposon, designated Tn6450, was characterized in a Proteus mirabilis isolate from chicken in China. Tn6450 contains 18 different antimicrobial resistance genes, including cephalosporinase gene blaDHA-1 and fluoroquinolone resistance genes qnrA1 and aac(6')-Ib-cr It carries a class 1/2 hybrid integron composed of intI2 and a 3' conserved segment of the class 1 integron. Tn6450 is derived from Tn7 via acquisition of new mobile elements and resistance genes. Copyright © 2018 American Society for Microbiology.

Journal: Antimicrobial agents and chemotherapy
DOI: 10.1128/AAC.02192-17
Year: 2018

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