July 7, 2019  |  

The birth of the Epitranscriptome: deciphering the function of RNA modifications.

Authors: Saletore, Yogesh and Meyer, Kate and Korlach, Jonas and Vilfan, Igor D and Jaffrey, Samie and Mason, Christopher E

Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.

Journal: Genome biology
DOI: 10.1186/gb-2012-13-10-175
Year: 2012

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