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July 7, 2019

Synchronous intramolecular cycloadditions of the polyene macrolactam polyketide heronamide C.

Authors: Booth, Thomas J and Alt, Silke and Capon, Robert J and Wilkinson, Barrie

A growing number of natural products appear to arise from biosynthetic pathways that involve pericyclic reactions. We show here that for the heronamides this can occur via two spontaneous pathways involving alternative thermal or photochemical intramolecular cycloadditions.

Journal: Chemical communications
DOI: 10.1039/c6cc01930g
Year: 2016

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