July 7, 2019  |  

IncHI2 plasmids are the key vectors responsible for oqxAB transmission among Salmonella species.

Authors: Wong, Marcus Ho-Yin and Chan, Edward Wai-Chi and Xie, Liqi and Li, Ruichao and Chen, Sheng

This study reported and analysed the complete sequences of two oqxAB-bearing IncHI2 plasmids harboured by a clinical S. Typhimurium strain and an S. Indiana strain of animal origin, respectively. Particularly, pA3T recovered from S. Indiana comprised the resistance determinants oqxAB, aac(6')Ib-cr, fosA3 and blaCTX-M-14 Further genetic screening of 63 oqxAB-positive Salmonella spp. isolates revealed that the majority carried IncHI2 plasmids, confirming that such plasmids play a pivotal role in dissemination of oqxAB in Salmonella spp.. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Journal: Antimicrobial agents and chemotherapy
DOI: 10.1128/AAC.01555-16
Year: 2016

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