July 7, 2019  |  

Genetic and functional characterization of blaCTX-M-199, a novel tazobactam and sulbactam resistance-encoding gene located in a conjugative mcr-1-bearing IncI2 plasmid.

Authors: Cai, Jiachang and Cheng, Qipeng and Shen, Yingbo and Gu, Danxia and Fang, Ying and Chan, Edward Wai-Chi and Chen, Sheng

The study reported the genetic and functional characterization of a novel CTX-M-199 ß-lactamase, which was encoded by a blaCTX-M-64 variant gene found in a conjugative mcr-1-bearing IncI2 plasmid and exhibited resistance to ß-lactamase inhibitors, tazobactam and sulbactam. Copyright © 2017 American Society for Microbiology.

Journal: Antimicrobial agents and chemotherapy
DOI: 10.1128/AAC.00562-17
Year: 2017

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