September 22, 2019  |  

Fungal Epigenomics: Detection and Analysis.

Authors: Mondo, Stephen J and Kuo, Rita C and Singan, Vasanth R

Across Eukaryota, DNA modifications play an important role in regulation of gene expression. While 5-methylcytosine (5mC) has been explored in depth, other modifications such as 6-methyladenine (6 mA) have historically been overlooked, in part due to technical difficulties in collecting/analyzing these data. However, recent technological advances have enabled exploration of these marks with much greater detail and on a larger scale. In this chapter, we discuss multiple methods for identifying and analyzing both 5mC and 6 mA across fungi.

Journal: Methods in molecular biology
DOI: 10.1007/978-1-4939-7804-5_14
Year: 2018

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