Detection and genetic features of MCR-1-producing plasmid in human Escherichia coli infection in South Korea.

Authors: Kim, Eun Sil and Chong, Yong Pil and Park, Su-Jin and Kim, Mi-Na and Kim, Sung-Han and Lee, Sang-Oh and Choi, Sang-Ho and Woo, Jun Hee and Jeong, Jin-Yong and Kim, Yang Soo

The plasmid-mediated colistin resistance gene, mcr-1, was identified for the first time from a hospitalized patient in South Korea. The mcr-1 gene was successfully transferred to E. coli J53 recipient and conferred resistance to colistin in the recipient. The mcr-1-harboring plasmid possessed a typical IncI2 group and did not have the mcr-1-associated ISApl1 element. Copyright © 2017 Elsevier Inc. All rights reserved.

Journal: Diagnostic microbiology and infectious disease
DOI: 10.1016/j.diagmicrobio.2017.06.020
Year: 2017

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