Complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic Leptospira interrogans serovar Manilae strain UP-MMC-NIID, originally isolated from a patient with severe leptospirosis, determined using PacBio Single-Molecule Real-Time technology.

Authors: Satou, Kazuhito and Shimoji, Makiko and Tamotsu, Hinako and Juan, Ayaka and Ashimine, Noriko and Shinzato, Misuzu and Toma, Claudia and Nohara, Toshitsugu and Shiroma, Akino and Nakano, Kazuma and Teruya, Kuniko and Terabayashi, Yasunobu and Ohki, Shun and Koizumi, Nobuo and Okano, Shou and Suzuki, Toshihiko and Hirano, Takashi

Here, we report the complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic Leptospira interrogans serovar Manilae strain UP-MMC-NIID, a major causative agent of leptospirosis. While there were no major differences between the genome sequences, the levels of base modifications were higher in the avirulent variant. Copyright © 2015 Satou et al.

Journal: Genome announcements
DOI: 10.1128/genomeA.00882-15
Year: 2015

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