Characterization of an IncA/C multidrug resistance plasmid in Vibrio alginolyticus.

Authors: Ye, Lianwei and Li, Ruichao and Lin, Dachuan and Zhou, Yuanjie and Fu, Aisi and Ding, Qiong and Chan, Edward Wai Chi and Yao, Wen and Chen, Sheng

Cephalosporin-resistant Vibrio alginolyticus were firstly isolated from food products with ß-lactamases, blaPER-1, blaVEB-1 and blaCMY-2, being the major mechanisms mediating cephalosporin resistance. The complete sequence of a multidrug resistance plasmid, pVAS3-1, harboring the blaCMY-2 and qnrVC4 genes was decoded in this study. Its backbone exhibited genetic homology to known IncA/C plasmids recoverable from Enterobacteriaceae species, suggesting its possible origin from Enterobacteriaceae. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Journal: Antimicrobial agents and chemotherapy
DOI: 10.1128/AAC.00300-16
Year: 2016

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