July 19, 2019  |  

An adenine code for DNA: A second life for N6-methyladenine.

Authors: Heyn, Holger and Esteller, Manel

DNA N6-methyladenine (6mA) protects against restriction enzymes in bacteria. However, isolated reports have suggested additional activities and its presence in other organisms, such as unicellular eukaryotes. New data now find that 6mA may have a gene regulatory function in green alga, worm, and fly, suggesting m6A as a potential "epigenetic" mark. Copyright © 2015 Elsevier Inc. All rights reserved.

Journal: Cell
DOI: 10.1016/j.cell.2015.04.021
Year: 2015

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