A simple thermoplastic substrate containing hierarchical silica lamellae for high-molecular-weight DNA extraction.

Authors: Zhang, Ye and Zhang, Yi and Burke, Jeffrey M and Gleitsman, Kristin and Friedrich, Sarah M and Liu, Kelvin J and Wang, Tza-Huei

An inexpensive, magnetic thermoplastic nanomaterial is developed utilizing a hierarchical layering of micro- and nanoscale silica lamellae to create a high-surface-area and low-shear substrate capable of capturing vast amounts of ultrahigh-molecular-weight DNA. Extraction is performed via a simple 45 min process and is capable of achieving binding capacities up to 1 000 000 times greater than silica microparticles. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Journal: Advanced materials
DOI: 10.1002/adma.201603738
Year: 2016

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