June 1, 2021

De novo assembly and preliminary annotation of the Schizocardium californicum genome

Author(s): Concepion, C., and Peluso, P., and Bump, P., and Gonzalez, P., and Lowe, C., and Rokhsar, D., and Rank, D.

Animals in the phylum Hemichordata have provided key understanding of the origins and development of body patterning and nervous system organization. However, efforts to sequence and assemble the genomes of highly heterozygous non-model organisms have proven to be difficult with traditional short read approaches. Long repetitive DNA structures, extensive structural variation between haplotypes in polyploid species, and large genome sizes are limiting factors to achieving highly contiguous genome assemblies. Here we present the highly contiguous de novo assembly and preliminary annotation of an indirect developing hemichordate genome, Schizocardium californicum, using SMRT Sequening long reads.

Organization: PacBio
Year: 2018

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