Blog
May 1, 2017
SMRT Sequencing Enables Accurate Calling of Pathogenic Variants in Medically Relevant Genes
Screening for pathogenic variants associated with polycystic kidney disease is now more accurate and affordable with SMRT Sequencing. A new paper in Human Mutation from scientists at Leiden University Medical…
April 25, 2017
Happy DNA Day! A Celebration of Great Science
It’s DNA Day, the annual celebration of the discovery of the double helix, the completion of the Human Genome Project, and all things genetic. We like to take the opportunity…
April 22, 2017
On Earth Day, a Shout Out to the Conservation Genomics Community
Today is Earth Day, a great time to reflect on the growing trend of conversation genomics. We are proud that many scientists are using PacBio long-read sequencing for the goal…
April 21, 2017
Review Paper Showcases Clinical Applications for SMRT Sequencing
Researchers from the Okinawa Institute of Advanced Sciences published a compelling review article describing several recent clinically relevant projects they have completed using SMRT Sequencing. Released in the journal Human…
April 13, 2017
New QC pipeline for Iso-Seq data increases confidence in transcript results
A preprint from scientists at the University of Florida, Centro de Investigaciones Principe Felipe, and other institutes describes a new analysis tool to help boost quality of transcriptome studies. “SQANTI:…
April 11, 2017
Crow Genome Analysis Combines Assemblies to Spot Tandem Arrays
A new publication in Genome Research shows how the use of SMRT Sequencing, in combination with other technologies, can reveal far more about repetitive DNA and structural variants than short-read…
April 10, 2017
Network with the SMRT Community at Our Upcoming User Group Meetings & Events
We are excited to announce our 2017 series of SMRT Community Events and User Group Meetings (UGMs), where you can learn first-hand how members of the scientific community are leveraging…
March 30, 2017
At AACR, Revealing Structural Variants and a New SMRT Grant Program
We’re excited to be heading to Washington, DC, for the annual meeting of the American Association for Cancer Research. The PacBio team always enjoys hearing about the latest in cancer…
March 29, 2017
IGV 3 Improves Support for PacBio Long Reads
The recent beta release of version 3 of the popular genome browser IGV greatly improves support for PacBio data [1]. The long reads (up to 50 kb) and random error…
March 27, 2017
Scientists Confirm Transplant-Associated Infection with SMRT Sequencing
A new PLoS One publication cites the use of SMRT Sequencing to clarify the transmission path of infection in a transplant recipient. This work is an excellent example of the…
March 23, 2017
Metal-Devouring Plant Genomes Get SMRT Treatment with Sequel System: 2016 SMRT Grant Program Winner Results
Blog readers may recall that last year’s SMRT Grant winner was Renying Zhuo from the Chinese Academy of Forestry. We’re pleased to report that the project is now complete! Zhuo…
March 21, 2017
New Goat Genome Assembly Breaks Continuity Record, Expands Breeding Tools
Efforts to produce a reference-grade goat genome assembly for improved breeding programs have paid off. A new Nature Genetics publication reports a high-quality, highly contiguous assembly that can be used…
March 16, 2017
Vote for the World’s Most Interesting Genome! Snakes, Slugs, Pigeons, Beetles & Dingoes Compete for SMRT Sequencing Treatment
Our team of scientist reviewers has considered hundreds of submissions for the latest SMRT Grant award and narrowed the selection to five finalists. Now it’s your turn! We welcome the…
March 7, 2017
High-Quality, Chromosome-Scale Quinoa Genome Valuable for Breeding Better Crops
A new genome assembly has remarkable promise to boost the global food supply. Scientists from King Abdullah University of Science and Technology and other institutions sequenced quinoa, a nutritious grain…
March 3, 2017
‘Mobilome’ Study of Antibiotic Resistance Implicates Transposon Activity
A recent effort to understand the genetic mechanisms behind swappable elements of drug-resistance among bacteria built on previous studies of Enterobacteriaceae isolates collected at the National Institutes of Health Clinical Center….